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Conversion surgery for unresectable pancreatic ductal adenocarcinoma with liver metastasis at initial diagnosis: a nationwide multicenter study.

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Title: Conversion surgery for unresectable pancreatic ductal adenocarcinoma with liver metastasis at initial diagnosis: a nationwide multicenter study.
Authors: Hashimoto D; Department of Pancreatobiliary Surgery, Kansai Medical University, Hirakata, Japan., Ikeura T; Third Department of Internal Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan. ikeurat@hirakata.kmu.ac.jp., Maekawa A; Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto City, Japan., Nakajima T; Department of Surgery, Meiwa Hospital, Nishinomiya, Japan., Ishido K; Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Hayasaki A; Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University, Tsu, Japan., Asano T; Department of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan., Hayashi M; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan., Yoshioka I; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan., Ishii H; Department of Surgery, Matsushita Memorial Hospital, Moriguchi, Japan., Kimura A; Department of Hepato- Biliary- Pancreatic Surgery and Pediatric Surgery, Saitama Medical University, Saitama, Japan., Motobayashi H; Second Department of Surgery, Wakayama Medical University, Wakayama, Japan., Murakawa M; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan., Okada K; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima, Japan., Abe T; Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan., Hirooka Y; Department of Gastroenterology and Hepatology, Fujita Health University, Toyoake, Japan., Imamura M; Division of Gastroenterological Surgery, Department of Surgery, Sapporo Medical University, Sapporo, Japan., Kamei K; Department of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan., Kobayashi S; Department of Gastroenterological Surgery, Osaka University, Suita, Japan., Maruo T; Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan., Matsumoto J; Department of General Surgery, Tonan Hospital, Sapporo, Japan., Miyabe K; Department of Gastroenterology, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan., Nagai M; Department of Surgery, Nara Medical University, Kashihara, Japan., Nakashima S; Department of Gastroenterological Surgery, Higashiosaka City Medical Center, Higashiosaka, Japan., Shindo Y; Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan., Shinzeki M; Department of Surgery, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan., Suzuki S; Department of Gastroenterological Surgery, Ibaraki Medical Center, Tokyo Medical University, Ibaraki, Japan., Suzuki T; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Bunkyo City, Japan., Tanaka M; Department of Surgery, Keio University School of Medicine, Shinjuku City, Japan., Tanno S; Department of Gastroenterology, IMS Sapporo Digestive Disease Center General Hospital, Sapporo, Japan., Yokota T; Center for Liver - Biliary - Pancreatic Diseases, Matsuyama Red Cross Hospital, Matsuyama, Japan., Murotani K; Biostatistics Center, Kurume University, Kurume, Japan., Nakai Y; Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Shinjuku City, Japan., Inoue Y; Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto City, Japan., Mizuma M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Unno M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Matsumoto I; Department of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan., Fujii T; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan., Uemura K; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima, Japan., Sho M; Department of Surgery, Nara Medical University, Kashihara, Japan., Hirano S; Department of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan., Satoi S; Department of Pancreatobiliary Surgery, Kansai Medical University, Hirakata, Japan.; Division of Surgical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Masamune A; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan., Takeyama Y; Department of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan.
Corporate Authors: A project study group of the Japan Pancreas Society
Source: Journal of gastroenterology [J Gastroenterol] 2026 May 04. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Conversion surgery for unresectable pancreatic ductal adenocarcinoma with liver metastasis at initial diagnosis: a nationwide multicenter study.
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  Data: <searchLink fieldCode="AU" term="%22Hashimoto+D%22">Hashimoto D</searchLink>; Department of Pancreatobiliary Surgery, Kansai Medical University, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeura+T%22">Ikeura T</searchLink>; Third Department of Internal Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan. ikeurat@hirakata.kmu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Maekawa+A%22">Maekawa A</searchLink>; Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto City, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+T%22">Nakajima T</searchLink>; Department of Surgery, Meiwa Hospital, Nishinomiya, Japan.<br /><searchLink fieldCode="AU" term="%22Ishido+K%22">Ishido K</searchLink>; Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Hayasaki+A%22">Hayasaki A</searchLink>; Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University, Tsu, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+T%22">Asano T</searchLink>; Department of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+M%22">Hayashi M</searchLink>; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshioka+I%22">Yoshioka I</searchLink>; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Ishii+H%22">Ishii H</searchLink>; Department of Surgery, Matsushita Memorial Hospital, Moriguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+A%22">Kimura A</searchLink>; Department of Hepato- Biliary- Pancreatic Surgery and Pediatric Surgery, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Motobayashi+H%22">Motobayashi H</searchLink>; Second Department of Surgery, Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Murakawa+M%22">Murakawa M</searchLink>; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Okada+K%22">Okada K</searchLink>; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima, Japan.<br /><searchLink fieldCode="AU" term="%22Abe+T%22">Abe T</searchLink>; Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Hirooka+Y%22">Hirooka Y</searchLink>; Department of Gastroenterology and Hepatology, Fujita Health University, Toyoake, Japan.<br /><searchLink fieldCode="AU" term="%22Imamura+M%22">Imamura M</searchLink>; Division of Gastroenterological Surgery, Department of Surgery, Sapporo Medical University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kamei+K%22">Kamei K</searchLink>; Department of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+S%22">Kobayashi S</searchLink>; Department of Gastroenterological Surgery, Osaka University, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Maruo+T%22">Maruo T</searchLink>; Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+J%22">Matsumoto J</searchLink>; Department of General Surgery, Tonan Hospital, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyabe+K%22">Miyabe K</searchLink>; Department of Gastroenterology, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Nagai+M%22">Nagai M</searchLink>; Department of Surgery, Nara Medical University, Kashihara, Japan.<br /><searchLink fieldCode="AU" term="%22Nakashima+S%22">Nakashima S</searchLink>; Department of Gastroenterological Surgery, Higashiosaka City Medical Center, Higashiosaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shindo+Y%22">Shindo Y</searchLink>; Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan.<br /><searchLink fieldCode="AU" term="%22Shinzeki+M%22">Shinzeki M</searchLink>; Department of Surgery, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+S%22">Suzuki S</searchLink>; Department of Gastroenterological Surgery, Ibaraki Medical Center, Tokyo Medical University, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+T%22">Suzuki T</searchLink>; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Bunkyo City, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+M%22">Tanaka M</searchLink>; Department of Surgery, Keio University School of Medicine, Shinjuku City, Japan.<br /><searchLink fieldCode="AU" term="%22Tanno+S%22">Tanno S</searchLink>; Department of Gastroenterology, IMS Sapporo Digestive Disease Center General Hospital, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Yokota+T%22">Yokota T</searchLink>; Center for Liver - Biliary - Pancreatic Diseases, Matsuyama Red Cross Hospital, Matsuyama, Japan.<br /><searchLink fieldCode="AU" term="%22Murotani+K%22">Murotani K</searchLink>; Biostatistics Center, Kurume University, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Nakai+Y%22">Nakai Y</searchLink>; Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Shinjuku City, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+Y%22">Inoue Y</searchLink>; Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto City, Japan.<br /><searchLink fieldCode="AU" term="%22Mizuma+M%22">Mizuma M</searchLink>; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Unno+M%22">Unno M</searchLink>; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+I%22">Matsumoto I</searchLink>; 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Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Takeyama+Y%22">Takeyama Y</searchLink>; Department of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan.
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