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Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population.

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Title: Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population.
Authors: Shiomi M; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Nagata Y; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan., Sudo T; Department of Educational Media Development, Institute of Science Tokyo, Tokyo, Japan., Takahashi K; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan., Higuchi C; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Ihara K; Department of Bio-informational Pharmacology, Medical Research Institute, Institute of Science Tokyo, Tokyo, Japan.; Department of Cardiovascular Medicine, Institute of Science Tokyo, Tokyo, Japan., Asada K; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan., Tanaka Y; Cardiovascular Center, Yokosuka Kyosai Hospital, Kanagawa, Japan., Yamauchi Y; Department of Cardiology, Yokohama City Minato Red Cross Hospital, Kanagawa, Japan., Sasaki T; Department of Cardiology, Heart Rhythm Center, National Hospital Organization Disaster Medical Center, Tokyo, Japan., Hachiya H; Cardiovascular Center, Tsuchiura Kyodo General Hospital, Ibaraki, Japan., Imai Y; Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, Japan., Fujita H; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan., Sasano T; Department of Cardiovascular Medicine, Institute of Science Tokyo, Tokyo, Japan., Furukawa T; Department of Bio-informational Pharmacology, Medical Research Institute, Institute of Science Tokyo, Tokyo, Japan., Tanaka T; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan.
Source: PloS one [PLoS One] 2026 May 04; Vol. 21 (5), pp. e0344360. Date of Electronic Publication: 2026 May 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population.
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  Data: <searchLink fieldCode="AU" term="%22Shiomi+M%22">Shiomi M</searchLink>; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nagata+Y%22">Nagata Y</searchLink>; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sudo+T%22">Sudo T</searchLink>; Department of Educational Media Development, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Higuchi+C%22">Higuchi C</searchLink>; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ihara+K%22">Ihara K</searchLink>; Department of Bio-informational Pharmacology, Medical Research Institute, Institute of Science Tokyo, Tokyo, Japan.; Department of Cardiovascular Medicine, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Asada+K%22">Asada K</searchLink>; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; Cardiovascular Center, Yokosuka Kyosai Hospital, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Yamauchi+Y%22">Yamauchi Y</searchLink>; Department of Cardiology, Yokohama City Minato Red Cross Hospital, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Sasaki+T%22">Sasaki T</searchLink>; Department of Cardiology, Heart Rhythm Center, National Hospital Organization Disaster Medical Center, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hachiya+H%22">Hachiya H</searchLink>; Cardiovascular Center, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Imai+Y%22">Imai Y</searchLink>; Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+H%22">Fujita H</searchLink>; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Sasano+T%22">Sasano T</searchLink>; Department of Cardiovascular Medicine, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Furukawa+T%22">Furukawa T</searchLink>; Department of Bio-informational Pharmacology, Medical Research Institute, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.; Bioresource Research Support Center, Institute of Science Tokyo, Tokyo, Japan.
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