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Effect of Nicotinamide Mononucleotide on Retinal Thickness of Older Patients With Diabetes Mellitus: A Placebo-Controlled, Double-Blind Study.

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Title: Effect of Nicotinamide Mononucleotide on Retinal Thickness of Older Patients With Diabetes Mellitus: A Placebo-Controlled, Double-Blind Study.
Authors: Shiraki A; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan., Hara C; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan., Akasaka H; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan., Nakagami H; Department of Health Development and Medicine, The University of Osaka Hospital, Osaka, Japan., Sugimoto K; Department of General Geriatric Medicine, Kawasaki Medical School, Okayama, Japan., Yasunobe Y; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan., Minami T; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan., Fujimoto T; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan., Yamamoto K; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan., Asano K; Academic Clinical Research Center, Department of Medical Innovation, Osaka University Hospital, Suita, Japan., Kanou M; Nutraceutical Group, Division of New Business Development Unit, Teijin Ltd., Chiyoda, Japan.; NOMON Co., Ltd., Tokyo, Japan., Yamana K; NOMON Co., Ltd., Tokyo, Japan.; Healthcare New Business CTO, Teijin Ltd., Chiyoda, Japan., Imai SI; Department of Developmental Biology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Rakugi H; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.; Osaka Rosai Hospital, Sakai, Japan., Nishida K; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Suita, Japan.
Source: Geriatrics & gerontology international [Geriatr Gerontol Int] 2026 May; Vol. 26 (5), pp. e70516.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Japan Geriatrics Society Country of Publication: Japan NLM ID: 101135738 Publication Model: Print Cited Medium: Internet ISSN: 1447-0594 (Electronic) Linking ISSN: 14470594 NLM ISO Abbreviation: Geriatr Gerontol Int Subsets: MEDLINE
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  Data: Effect of Nicotinamide Mononucleotide on Retinal Thickness of Older Patients With Diabetes Mellitus: A Placebo-Controlled, Double-Blind Study.
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  Data: <searchLink fieldCode="AU" term="%22Shiraki+A%22">Shiraki A</searchLink>; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hara+C%22">Hara C</searchLink>; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Akasaka+H%22">Akasaka H</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagami+H%22">Nakagami H</searchLink>; Department of Health Development and Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Sugimoto+K%22">Sugimoto K</searchLink>; Department of General Geriatric Medicine, Kawasaki Medical School, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Yasunobe+Y%22">Yasunobe Y</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Minami+T%22">Minami T</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fujimoto+T%22">Fujimoto T</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+K%22">Yamamoto K</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+K%22">Asano K</searchLink>; Academic Clinical Research Center, Department of Medical Innovation, Osaka University Hospital, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Kanou+M%22">Kanou M</searchLink>; Nutraceutical Group, Division of New Business Development Unit, Teijin Ltd., Chiyoda, Japan.; NOMON Co., Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamana+K%22">Yamana K</searchLink>; NOMON Co., Ltd., Tokyo, Japan.; Healthcare New Business CTO, Teijin Ltd., Chiyoda, Japan.<br /><searchLink fieldCode="AU" term="%22Imai+SI%22">Imai SI</searchLink>; Department of Developmental Biology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Rakugi+H%22">Rakugi H</searchLink>; Department of Geriatric and General Medicine, The University of Osaka Hospital, Osaka, Japan.; Osaka Rosai Hospital, Sakai, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+K%22">Nishida K</searchLink>; Department of Ophthalmology, The University of Osaka Hospital, Osaka, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Suita, Japan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Japan+Geriatrics+Society%22">Japan Geriatrics Society </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>101135738 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1447-0594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214470594%22">14470594 </searchLink><i>NLM ISO Abbreviation: </i>Geriatr Gerontol Int <i>Subsets: </i>MEDLINE
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