Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol.
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| Title: | Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol. |
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| Authors: | Marchand LS; Department of Orthopaedic Surgery, University of Utah, Salt Lake City, Utah, USA lucas.marchand@hsc.utah.edu., Slobogean G; Department of Orthopedic Surgery, University of California, Irvine, Orange, California, USA., O'Hara NN; Department of Orthopaedics, University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Center for Orthopaedic Injury Research and Innovation, Baltimore, Maryland, USA., Harris AD; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA., Grainger DW; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA., Thabane L; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Bhandari M; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Della Rocca GJ; Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA., Kellam PJ; Department of Orthopedic Surgery, McGovern Medical School at UTHealth Houston, Houston, Texas, USA., Zura RD; LSUHSC Orthopaedics New Orleans, New Orleans, Louisiana, USA., Marvel D; Patient Representative, University of Maryland Baltimore, Baltimore, Maryland, USA., Wells JL; Patient Representative, University of Maryland Baltimore, Baltimore, Maryland, USA., Gitajn IL; Department of Orthopaedic Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA., Jeray KJ; Department of Orthopedic Surgery, Prisma Health-Upstate, University of South Carolina, Greenville, South Carolina, USA., O'Toole RV; Department of Orthopaedics, University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Center for Orthopaedic Injury Research and Innovation, Baltimore, Maryland, USA., Working ZM; Department of Orthopaedics & Rehabilitation, Oregon Health & Science University, Portland, Oregon, USA., Natoli RM; Division of Orthopaedic Trauma, Department of Orthopaedic Surgery, IU Methodist Hospital, Indianapolis, Indiana, USA., Bergin PF; Department of Orthopaedic Surgery and Rehabilitation, University of Mississippi Medical Center, Jackson, Mississippi, USA., Hagen JE; Division of Orthopaedic Trauma, Department of Orthopaedic Surgery and Sports Medicine, University of Florida, Gainesville, Florida, USA., Levack AE; Department of Orthopaedic Surgery & Rehabilitation, Loyola University Medical Center & Stritch School of Medicine, Maywood, Illinois, USA., Guerra-Farfan E; Department of Orthopedic Surgery and Traumatology, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Schrank GM; Division of Infectious Disease, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA., Hebden JN; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA., Mossuto F; Division of Orthopaedic Surgery, Hamilton Health Sciences Hospital, General Site, Hamilton, Ontario, Canada., Tsoutsounakis C; University of Utah Hospital, Salt Lake City, Utah, USA., Pogorzelski D; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Pineda H; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Bzovsky S; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Sprague S; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.; Department of Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, Maryland, USA. |
| Corporate Authors: | BvV Investigators |
| Source: | BMJ open [BMJ Open] 2026 May 04; Vol. 16 (5), pp. e088521. Date of Electronic Publication: 2026 May 04. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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