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Complete pathologic response surrogacy for survival and its predictors in locally advanced rectal cancer: a retrospective cohort study.

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Title: Complete pathologic response surrogacy for survival and its predictors in locally advanced rectal cancer: a retrospective cohort study.
Authors: Ghalehtaki R; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Abyaneh R; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Salarvand S; Department of Pathology, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Rezaei S; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Sharifian A; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Bagheri F; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Nazari R; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Nabian N; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Naseri S; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Hoseini SM; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Nouranifar A; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Javid HR; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Mohammadi N; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Darzikolaee NM; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Behboudi B; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Tafti MA; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Fazeli M; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Keshvari A; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Kazemeini A; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Keramati M; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Pak H; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran., Babaei M; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Farhan F; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Saraee E; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Aghili M; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran. aghili@sina.tums.ac.ir.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran. aghili@sina.tums.ac.ir., Kolahdouzan K; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran. Kakol_72@yahoo.com.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Kakol_72@yahoo.com.
Source: International journal of colorectal disease [Int J Colorectal Dis] 2026 May 04; Vol. 41 (1). Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8607899 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1262 (Electronic) Linking ISSN: 01791958 NLM ISO Abbreviation: Int J Colorectal Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Complete pathologic response surrogacy for survival and its predictors in locally advanced rectal cancer: a retrospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Ghalehtaki+R%22">Ghalehtaki R</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Abyaneh+R%22">Abyaneh R</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Salarvand+S%22">Salarvand S</searchLink>; Department of Pathology, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Rezaei+S%22">Rezaei S</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Sharifian+A%22">Sharifian A</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Bagheri+F%22">Bagheri F</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Nazari+R%22">Nazari R</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Nabian+N%22">Nabian N</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Naseri+S%22">Naseri S</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Hoseini+SM%22">Hoseini SM</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Nouranifar+A%22">Nouranifar A</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Javid+HR%22">Javid HR</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Mohammadi+N%22">Mohammadi N</searchLink>; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Darzikolaee+NM%22">Darzikolaee NM</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Behboudi+B%22">Behboudi B</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Tafti+MA%22">Tafti MA</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Fazeli+M%22">Fazeli M</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Keshvari+A%22">Keshvari A</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Kazemeini+A%22">Kazemeini A</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Keramati+M%22">Keramati M</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Pak+H%22">Pak H</searchLink>; Division of Colorectal Surgery, Department of Surgery, IKHC, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Babaei+M%22">Babaei M</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Farhan+F%22">Farhan F</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Saraee+E%22">Saraee E</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Aghili+M%22">Aghili M</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran. aghili@sina.tums.ac.ir.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran. aghili@sina.tums.ac.ir.<br /><searchLink fieldCode="AU" term="%22Kolahdouzan+K%22">Kolahdouzan K</searchLink>; Department of Radiation Oncology, School of Medicine, Cancer Research Institute, IKHC, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran. Kakol_72@yahoo.com.; Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Kakol_72@yahoo.com.
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              Text: 2026 May 04
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