Optimizing mouse models for mRNA vaccines: addressing dose translation challenges.
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| Title: | Optimizing mouse models for mRNA vaccines: addressing dose translation challenges. |
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| Authors: | Chang ZW; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan YJ; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Liao Y; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore., Goh YS; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Kabir SR; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wang Y; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore., Hor PX; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Loh CY; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Huang Y; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang B; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Salleh SNM; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ngoh EZX; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang CI; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lye DC; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Communicable Diseases Agency, Singapore, Singapore., Young BE; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Tay MZ; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ng LFP; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ejima K; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Renia L; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. LCSRENIA@ntu.edu.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore. LCSRENIA@ntu.edu.sg.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. LCSRENIA@ntu.edu.sg.; National Centre for Infectious Diseases, Singapore, Singapore. LCSRENIA@ntu.edu.sg. |
| Corporate Authors: | COVID-19 Cohort Study Group, NCID Study Group, COVID-19 Clinicians’ Group |
| Source: | Scientific reports [Sci Rep] 2026 May 05. Date of Electronic Publication: 2026 May 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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