Costimulation loss enhances IL-2-driven Treg generation by PI3K-STAT3 inhibition in CNS autoimmunity.

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Title: Costimulation loss enhances IL-2-driven Treg generation by PI3K-STAT3 inhibition in CNS autoimmunity.
Authors: Nam KH; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea., Kim GR; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea.; Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea., Kim YR; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea., Kwon YN; Department of Neurology, Kangbuk Samsung Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Department of Neurology, Seoul National University Hospital, Seoul, Republic of Korea., Kim SM; Department of Neurology, Seoul National University, College of Medicine, Seoul, Republic of Korea., Choi JM; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Hanyang Institute of Bioscience and Biotechnology, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Research Institute for Convergence of Basic Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2272-2292. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: Costimulation loss enhances IL-2-driven Treg generation by PI3K-STAT3 inhibition in CNS autoimmunity.
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  Data: <searchLink fieldCode="AU" term="%22Nam+KH%22">Nam KH</searchLink>; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+GR%22">Kim GR</searchLink>; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea.; Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YR%22">Kim YR</searchLink>; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+YN%22">Kwon YN</searchLink>; Department of Neurology, Kangbuk Samsung Hospital, Seoul, Republic of Korea.; Biomedical Research Institute, Department of Neurology, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SM%22">Kim SM</searchLink>; Department of Neurology, Seoul National University, College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JM%22">Choi JM</searchLink>; Department of Life Science, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Hanyang Institute of Bioscience and Biotechnology, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.; Research Institute for Convergence of Basic Sciences, Hanyang University, Seoul, Republic of Korea. jeminchoi@hanyang.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2272-2292. <i>Date of Electronic Publication: </i>2026 May 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s44321-026-00431-7
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      – TitleFull: Costimulation loss enhances IL-2-driven Treg generation by PI3K-STAT3 inhibition in CNS autoimmunity.
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              Text: 2026 Jun
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