Lower-dose glucocorticoid therapy achieves comparable outcomes in Japanese patients with lupus nephritis.

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Title: Lower-dose glucocorticoid therapy achieves comparable outcomes in Japanese patients with lupus nephritis.
Authors: Abe Y; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan., Makiyama A; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan., Minowa K; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan., Uchiyama S; Clinical Research and Trial Center, Juntendo UniversityHospital, Tokyo, Japan., Kogami M; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan., Takeuchi M; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan., Tanaka Y; The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan., Hiromura K; Department of Nephrology and Rheumatology, Gunma UniversityGraduate School of Medicine, Maebashi, Japan., Hayashi H; Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Japan., Kamada K; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Kawahito Y; Inflammation and Immunology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Iwashita A; Department of Rheumatology and Clinical Immunology, Kyoto UniversityGraduate School of Medicine, Kyoto, Japan., Kaname S; Department of Nephrology and Rheumatology, Kyorin UniversitySchool of Medicine, Mitaka, Japan.; Department of Internal Medicine, Kichijoji Asahi Hospital, Tokyo, Japan., Shimizu H; Department of Rheumatology, Kobe City Medical Center General Hospital, Kobe, Japan.; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Japan., Yasuda S; Department of Rheumatology, Institute of Science Tokyo, Tokyo, Japan., Hiramoto K; Division of Rheumatology, Department of Internal Medicine, Keio UniversitySchool of Medicine, Tokyo, Japan., Maruyama S; Department of Nephrology, Nagoya UniversityGraduate School of Medicine, Nagoya, Japan., Yajima N; Division of Rheumatology, Department of Medicine, Showa Medical University, Tokyo, Japan., Iwata Y; Department of Nephrology and Rheumatology, Kanazawa University, Kanazawa, Japan., Matsumoto I; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Gono T; Department of Allergy and Rheumatology, Nippon Medical SchoolGraduate School of Medicine, Tokyo, Japan.; Scleroderma/Myositis Center of Excellence, Nippon Medical SchoolHospital, Tokyo, Japan., Sato H; Department of Rheumatology, Tohoku UniversityHospital, Sendai, Japan., Kubo S; The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan., Ikeuchi H; Department of Nephrology and Rheumatology, Gunma UniversityGraduate School of Medicine, Maebashi, Japan., Yuzawa Y; Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Japan., Kono M; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Seno T; Inflammation and Immunology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Onishi A; Department of Advanced Medicine for Rheumatic Diseases, Kyoto UniversityGraduate School of Medicine, Kyoto, Japan., Kawakami T; Department of Nephrology and Rheumatology, Kyorin UniversitySchool of Medicine, Mitaka, Japan., Hosoya T; Department of Rheumatology, Institute of Science Tokyo, Tokyo, Japan., Kaneko Y; Division of Rheumatology, Department of Internal Medicine, Keio UniversitySchool of Medicine, Tokyo, Japan., Kato S; Department of Nephrology, Nagoya UniversityGraduate School of Medicine, Nagoya, Japan., Nakagawa S; Department of Nephrology and Rheumatology, Kanazawa University, Kanazawa, Japan., Kondo Y; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Kuwana M; Department of Allergy and Rheumatology, Nippon Medical SchoolGraduate School of Medicine, Tokyo, Japan.; Scleroderma/Myositis Center of Excellence, Nippon Medical SchoolHospital, Tokyo, Japan., Ishii T; Department of Rheumatology, Tohoku UniversityHospital, Sendai, Japan.; Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan., Atsumi T; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Ohmura K; Department of Rheumatology, Kobe City Medical Center General Hospital, Kobe, Japan., Tamura N; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.
Source: Lupus [Lupus] 2026 Jul; Vol. 35 (8), pp. 831-841. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9204265 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0962 (Electronic) Linking ISSN: 09612033 NLM ISO Abbreviation: Lupus Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lower-dose glucocorticoid therapy achieves comparable outcomes in Japanese patients with lupus nephritis.
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  Data: <searchLink fieldCode="AU" term="%22Abe+Y%22">Abe Y</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Makiyama+A%22">Makiyama A</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Minowa+K%22">Minowa K</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Uchiyama+S%22">Uchiyama S</searchLink>; Clinical Research and Trial Center, Juntendo UniversityHospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kogami+M%22">Kogami M</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+M%22">Takeuchi M</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Hiromura+K%22">Hiromura K</searchLink>; Department of Nephrology and Rheumatology, Gunma UniversityGraduate School of Medicine, Maebashi, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+H%22">Hayashi H</searchLink>; Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Japan.<br /><searchLink fieldCode="AU" term="%22Kamada+K%22">Kamada K</searchLink>; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahito+Y%22">Kawahito Y</searchLink>; Inflammation and Immunology, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Iwashita+A%22">Iwashita A</searchLink>; Department of Rheumatology and Clinical Immunology, Kyoto UniversityGraduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kaname+S%22">Kaname S</searchLink>; Department of Nephrology and Rheumatology, Kyorin UniversitySchool of Medicine, Mitaka, Japan.; Department of Internal Medicine, Kichijoji Asahi Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shimizu+H%22">Shimizu H</searchLink>; Department of Rheumatology, Kobe City Medical Center General Hospital, Kobe, Japan.; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Yasuda+S%22">Yasuda S</searchLink>; Department of Rheumatology, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hiramoto+K%22">Hiramoto K</searchLink>; Division of Rheumatology, Department of Internal Medicine, Keio UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Maruyama+S%22">Maruyama S</searchLink>; Department of Nephrology, Nagoya UniversityGraduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Yajima+N%22">Yajima N</searchLink>; Division of Rheumatology, Department of Medicine, Showa Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Iwata+Y%22">Iwata Y</searchLink>; Department of Nephrology and Rheumatology, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+I%22">Matsumoto I</searchLink>; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Gono+T%22">Gono T</searchLink>; Department of Allergy and Rheumatology, Nippon Medical SchoolGraduate School of Medicine, Tokyo, Japan.; Scleroderma/Myositis Center of Excellence, Nippon Medical SchoolHospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+H%22">Sato H</searchLink>; Department of Rheumatology, Tohoku UniversityHospital, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Kubo+S%22">Kubo S</searchLink>; The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeuchi+H%22">Ikeuchi H</searchLink>; 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Department of Rheumatology, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneko+Y%22">Kaneko Y</searchLink>; Division of Rheumatology, Department of Internal Medicine, Keio UniversitySchool of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+S%22">Kato S</searchLink>; Department of Nephrology, Nagoya UniversityGraduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagawa+S%22">Nakagawa S</searchLink>; Department of Nephrology and Rheumatology, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+Y%22">Kondo Y</searchLink>; Department of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kuwana+M%22">Kuwana M</searchLink>; Department of Allergy and Rheumatology, Nippon Medical SchoolGraduate School of Medicine, Tokyo, Japan.; Scleroderma/Myositis Center of Excellence, Nippon Medical SchoolHospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ishii+T%22">Ishii T</searchLink>; Department of Rheumatology, Tohoku UniversityHospital, Sendai, Japan.; Tohoku Medical and Pharmaceutical University Hospital, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Atsumi+T%22">Atsumi T</searchLink>; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohmura+K%22">Ohmura K</searchLink>; Department of Rheumatology, Kobe City Medical Center General Hospital, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Tamura+N%22">Tamura N</searchLink>; Department of Internal Medicine and Rheumatology, Juntendo UniversitySchool of Medicine, Tokyo, Japan.
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