Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS.
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| Title: | Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS. |
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| Authors: | Hammers DB; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Polsinelli A; Department of Psychology Simon Frasier University Vancouver British Columbia Canada., Eloyan A; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA., Taurone A; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA., Thangarajah M; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA., Foroud T; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA., Gao S; Department of Biostatistics Indiana University School of Medicine Indianapolis Indiana USA., Beckett L; Department of Public Health Sciences University of California - Davis Davis California USA., La Joie R; Department of Neurology University of California - San Francisco San Francisco California USA., Touroutoglou A; Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA., Vemuri P; Department of Neurology Mayo Clinic Rochester Minnesota USA., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology The Sahlgrenska Academy, University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Pathology and Laboratory Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK., Blennow K; Eli Lilly and Company Indianapolis Indiana USA., Nemes S; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Kostadinova R; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Aisen P; Alzheimer's Therapeutic Research Institute University of Southern California San Diego California USA., Nudelman KN; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA., Kirby K; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Atri A; Banner Sun Health Research Institute Sun City Arizona USA., Clark D; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Day GS; Department of Neurology Mayo Clinic Jacksonville Florida USA., Duara R; Wien Center for Alzheimer's Disease and Memory Disorders Mount Sinai Medical Center Miami Florida USA., Graff-Radford NR; Department of Neurology Mayo Clinic Jacksonville Florida USA., Grant I; Department of Psychiatry and Behavioral Sciences Mesulam Center for Cognitive Neurology and Alzheimer's Disease Feinberg School of Medicine Northwestern University Chicago Illinois USA., Honig LS; Taub Institute and Department of Neurology Columbia University Irving Medical Center New York New York USA., Johnson ECB; Department of Neurology and Human Genetics Emory University School of Medicine Atlanta Georgia USA., Jones DT; Department of Neurology Mayo Clinic Rochester Minnesota USA., Masdeu JC; Nantz National Alzheimer Center Houston Methodist and Weill Cornell Medicine Houston Texas USA., Mendez MF; Department of Neurology David Geffen School of Medicine at UCLA Los Angeles California USA., Parand L; Department of Neurology David Geffen School of Medicine at UCLA Los Angeles California USA., Womack K; Department of Neurology Washington University in St. Louis St. Louis Missouri USA., Musiek E; Department of Neurology Washington University in St. Louis St. Louis Missouri USA., Onyike CU; Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine Baltimore Maryland USA., Riddle M; Department of Neurology Alpert Medical School, Brown University Providence Rhode Island USA., Rogalski E; Healthy Aging & Alzheimer's Research Care Center, Department of Neurology University of Chicago Chicago Illinois USA., Salloway S; Department of Neurology Alpert Medical School, Brown University Providence Rhode Island USA., Sha SJ; Department of Neurology & Neurological Sciences Stanford University Palo Alto California USA., Turner RS; Department of Neurology Georgetown University Washington D.C. USA., Wingo TS; Department of Neurology UC Davis Alzheimer's Disease Research Center University of California - Davis Davis California USA., Wolk DA; Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA., Carrillo MC; Medical & Scientific Relations Division Alzheimer's Association Chicago Illinois USA., Rabinovici GD; Department of Neurology University of California - San Francisco San Francisco California USA., Dickerson BC; Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA., Dage JL; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA., Apostolova LG; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA.; Department of Radiology and Imaging Sciences Center for Neuroimaging Indiana University School of Medicine Indianapolis Indianapolis Indiana USA. |
| Corporate Authors: | LEADS Consortium |
| Source: | Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2026 May 03; Vol. 18, pp. e70342. Date of Electronic Publication: 2026 May 03 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101654604 Publication Model: eCollection Cited Medium: Print ISSN: 2352-8729 (Print) Linking ISSN: 23528729 NLM ISO Abbreviation: Alzheimers Dement (Amst) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42088846 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hammers+DB%22">Hammers DB</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Polsinelli+A%22">Polsinelli A</searchLink>; Department of Psychology Simon Frasier University Vancouver British Columbia Canada.<br /><searchLink fieldCode="AU" term="%22Eloyan+A%22">Eloyan A</searchLink>; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA.<br /><searchLink fieldCode="AU" term="%22Taurone+A%22">Taurone A</searchLink>; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA.<br /><searchLink fieldCode="AU" term="%22Thangarajah+M%22">Thangarajah M</searchLink>; Department of Biostatistics, Center for Statistical Sciences Brown University Providence Rhode Island USA.<br /><searchLink fieldCode="AU" term="%22Foroud+T%22">Foroud T</searchLink>; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Department of Biostatistics Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Beckett+L%22">Beckett L</searchLink>; Department of Public Health Sciences University of California - Davis Davis California USA.<br /><searchLink fieldCode="AU" term="%22La+Joie+R%22">La Joie R</searchLink>; Department of Neurology University of California - San Francisco San Francisco California USA.<br /><searchLink fieldCode="AU" term="%22Touroutoglou+A%22">Touroutoglou A</searchLink>; Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA.<br /><searchLink fieldCode="AU" term="%22Vemuri+P%22">Vemuri P</searchLink>; Department of Neurology Mayo Clinic Rochester Minnesota USA.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology The Sahlgrenska Academy, University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Pathology and Laboratory Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Eli Lilly and Company Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Nemes+S%22">Nemes S</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Kostadinova+R%22">Kostadinova R</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Aisen+P%22">Aisen P</searchLink>; Alzheimer's Therapeutic Research Institute University of Southern California San Diego California USA.<br /><searchLink fieldCode="AU" term="%22Nudelman+KN%22">Nudelman KN</searchLink>; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Kirby+K%22">Kirby K</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Atri+A%22">Atri A</searchLink>; Banner Sun Health Research Institute Sun City Arizona USA.<br /><searchLink fieldCode="AU" term="%22Clark+D%22">Clark D</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Day+GS%22">Day GS</searchLink>; Department of Neurology Mayo Clinic Jacksonville Florida USA.<br /><searchLink fieldCode="AU" term="%22Duara+R%22">Duara R</searchLink>; Wien Center for Alzheimer's Disease and Memory Disorders Mount Sinai Medical Center Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Graff-Radford+NR%22">Graff-Radford NR</searchLink>; Department of Neurology Mayo Clinic Jacksonville Florida USA.<br /><searchLink fieldCode="AU" term="%22Grant+I%22">Grant I</searchLink>; Department of Psychiatry and Behavioral Sciences Mesulam Center for Cognitive Neurology and Alzheimer's Disease Feinberg School of Medicine Northwestern University Chicago Illinois USA.<br /><searchLink fieldCode="AU" term="%22Honig+LS%22">Honig LS</searchLink>; Taub Institute and Department of Neurology Columbia University Irving Medical Center New York New York USA.<br /><searchLink fieldCode="AU" term="%22Johnson+ECB%22">Johnson ECB</searchLink>; Department of Neurology and Human Genetics Emory University School of Medicine Atlanta Georgia USA.<br /><searchLink fieldCode="AU" term="%22Jones+DT%22">Jones DT</searchLink>; Department of Neurology Mayo Clinic Rochester Minnesota USA.<br /><searchLink fieldCode="AU" term="%22Masdeu+JC%22">Masdeu JC</searchLink>; Nantz National Alzheimer Center Houston Methodist and Weill Cornell Medicine Houston Texas USA.<br /><searchLink fieldCode="AU" term="%22Mendez+MF%22">Mendez MF</searchLink>; Department of Neurology David Geffen School of Medicine at UCLA Los Angeles California USA.<br /><searchLink fieldCode="AU" term="%22Parand+L%22">Parand L</searchLink>; Department of Neurology David Geffen School of Medicine at UCLA Los Angeles California USA.<br /><searchLink fieldCode="AU" term="%22Womack+K%22">Womack K</searchLink>; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Musiek+E%22">Musiek E</searchLink>; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Onyike+CU%22">Onyike CU</searchLink>; Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine Baltimore Maryland USA.<br /><searchLink fieldCode="AU" term="%22Riddle+M%22">Riddle M</searchLink>; Department of Neurology Alpert Medical School, Brown University Providence Rhode Island USA.<br /><searchLink fieldCode="AU" term="%22Rogalski+E%22">Rogalski E</searchLink>; Healthy Aging & Alzheimer's Research Care Center, Department of Neurology University of Chicago Chicago Illinois USA.<br /><searchLink fieldCode="AU" term="%22Salloway+S%22">Salloway S</searchLink>; Department of Neurology Alpert Medical School, Brown University Providence Rhode Island USA.<br /><searchLink fieldCode="AU" term="%22Sha+SJ%22">Sha SJ</searchLink>; Department of Neurology & Neurological Sciences Stanford University Palo Alto California USA.<br /><searchLink fieldCode="AU" term="%22Turner+RS%22">Turner RS</searchLink>; Department of Neurology Georgetown University Washington D.C. USA.<br /><searchLink fieldCode="AU" term="%22Wingo+TS%22">Wingo TS</searchLink>; Department of Neurology UC Davis Alzheimer's Disease Research Center University of California - Davis Davis California USA.<br /><searchLink fieldCode="AU" term="%22Wolk+DA%22">Wolk DA</searchLink>; Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22Carrillo+MC%22">Carrillo MC</searchLink>; Medical & Scientific Relations Division Alzheimer's Association Chicago Illinois USA.<br /><searchLink fieldCode="AU" term="%22Rabinovici+GD%22">Rabinovici GD</searchLink>; Department of Neurology University of California - San Francisco San Francisco California USA.<br /><searchLink fieldCode="AU" term="%22Dickerson+BC%22">Dickerson BC</searchLink>; Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA.<br /><searchLink fieldCode="AU" term="%22Dage+JL%22">Dage JL</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.<br /><searchLink fieldCode="AU" term="%22Apostolova+LG%22">Apostolova LG</searchLink>; Department of Neurology Indiana University School of Medicine Indianapolis Indiana USA.; Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA.; Department of Radiology and Imaging Sciences Center for Neuroimaging Indiana University School of Medicine Indianapolis Indianapolis Indiana USA. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22LEADS+Consortium%22">LEADS Consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101654604%22">Alzheimer's & dementia (Amsterdam, Netherlands)</searchLink> [Alzheimers Dement (Amst)] 2026 May 03; Vol. 18, pp. e70342. <i>Date of Electronic Publication: </i>2026 May 03 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101654604 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2352-8729 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528729%22">23528729 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (Amst) <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42088846 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/dad2.70342 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e70342 Titles: – TitleFull: Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hammers DB – PersonEntity: Name: NameFull: Polsinelli A – PersonEntity: Name: NameFull: Eloyan A – PersonEntity: Name: NameFull: Taurone A – PersonEntity: Name: NameFull: Thangarajah M – PersonEntity: Name: NameFull: Foroud T – PersonEntity: Name: NameFull: Gao S – PersonEntity: Name: NameFull: Beckett L – PersonEntity: Name: NameFull: La Joie R – PersonEntity: Name: NameFull: Touroutoglou A – PersonEntity: Name: NameFull: Vemuri P – PersonEntity: Name: NameFull: Zetterberg H – PersonEntity: Name: NameFull: Blennow K – PersonEntity: Name: NameFull: Nemes S – PersonEntity: Name: NameFull: Kostadinova R – PersonEntity: Name: NameFull: Aisen P – PersonEntity: Name: NameFull: Nudelman KN – PersonEntity: Name: NameFull: Kirby K – PersonEntity: Name: NameFull: Atri A – PersonEntity: Name: NameFull: Clark D – PersonEntity: Name: NameFull: Day GS – PersonEntity: Name: NameFull: Duara R – PersonEntity: Name: NameFull: Graff-Radford NR – PersonEntity: Name: NameFull: Grant I – PersonEntity: Name: NameFull: Honig LS – PersonEntity: Name: NameFull: Johnson ECB – PersonEntity: Name: NameFull: Jones DT – PersonEntity: Name: NameFull: Masdeu JC – PersonEntity: Name: NameFull: Mendez MF – PersonEntity: Name: NameFull: Parand L – PersonEntity: Name: NameFull: Womack K – PersonEntity: Name: NameFull: Musiek E – PersonEntity: Name: NameFull: Onyike CU – PersonEntity: Name: NameFull: Riddle M – PersonEntity: Name: NameFull: Rogalski E – PersonEntity: Name: NameFull: Salloway S – PersonEntity: Name: NameFull: Sha SJ – PersonEntity: Name: NameFull: Turner RS – PersonEntity: Name: NameFull: Wingo TS – PersonEntity: Name: NameFull: Wolk DA – PersonEntity: Name: NameFull: Carrillo MC – PersonEntity: Name: NameFull: Rabinovici GD – PersonEntity: Name: NameFull: Dickerson BC – PersonEntity: Name: NameFull: Dage JL – PersonEntity: Name: NameFull: Apostolova LG IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 05 Text: 2026 May 03 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2352-8729 Numbering: – Type: volume Value: 18 Titles: – TitleFull: Alzheimer's & dementia (Amsterdam, Netherlands) Type: main |
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