CRISPR and compound screens in a novel ex vivo tissue model identify DDR1 and ETA as regulators of cancer cell invasion.
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| Title: | CRISPR and compound screens in a novel ex vivo tissue model identify DDR1 and ETA as regulators of cancer cell invasion. |
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| Authors: | Liu J; Department of Urology, Ulm University Hospital, Ulm, Germany.; Department of Urology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., Jiang W; Department of Urology, Ulm University Hospital, Ulm, Germany.; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY, USA., Wang X; Department of Urology, Ulm University Hospital, Ulm, Germany.; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY, USA.; Mol. Pharmacology and Exp. Therapeutics, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., Azoitei A; Department of Urology, Ulm University Hospital, Ulm, Germany., Liu H; Department of Urology, Ulm University Hospital, Ulm, Germany., Najjar G; Department of Urology, Ulm University Hospital, Ulm, Germany., Liu K; Department of Urology, Ulm University Hospital, Ulm, Germany., Melzer MK; Department of Urology, Ulm University Hospital, Ulm, Germany., Stilgenbauer S; Department of Internal Medicine III, Ulm University Hospital, Ulm, Germany., Elati M; CANTHER, ONCOLille Institute, University of Lille, CNRS UMR 1277, Inserm U9020, Lille, France., Burkhalter MD; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, Tübingen, Germany., Philipp M; Department of Experimental and Clinical Pharmacology and Pharmacogenomics, Section of Pharmacogenomics, Eberhard-Karls-University Tübingen, Tübingen, Germany., Wezel F; Department of Urology, Ulm University Hospital, Ulm, Germany., Zengerling F; Department of Urology, Ulm University Hospital, Ulm, Germany., Bolenz C; Department of Urology, Ulm University Hospital, Ulm, Germany. Christian.Bolenz@uniklinik-ulm.de., Günes C; Department of Urology, Ulm University Hospital, Ulm, Germany. Cagatay.Guenes@uni-ulm.de. |
| Source: | Cellular & molecular biology letters [Cell Mol Biol Lett] 2026 May 06; Vol. 31 (1). Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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