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CDK4/6 inhibitor ribociclib and doxorubicin combination treatment inhibits breast cancer bone metastasis and enhances T-cell targeted therapy.

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Title: CDK4/6 inhibitor ribociclib and doxorubicin combination treatment inhibits breast cancer bone metastasis and enhances T-cell targeted therapy.
Authors: Su X; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Kobayashi T; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Breast Medical Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan., Xiang J; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Xu Y; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Shajahan-Haq AN; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Mardani M; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Noordeen S; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., O'Donnell K; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Kwakwa KA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Guan D; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Fox GC; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Fontana F; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Cybulla E; Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210, USA., Bakewell S; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Vindigni A; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Veis DJ; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Musculoskeletal Research Center, Histology and Morphometry Core, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Achilefu S; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, TX 7530, USA., Lanza GM; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Weilbaecher KN; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Source: Journal of bone oncology [J Bone Oncol] 2026 Apr 25; Vol. 58, pp. 100765. Date of Electronic Publication: 2026 Apr 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101610292 Publication Model: eCollection Cited Medium: Print ISSN: 2212-1366 (Print) Linking ISSN: 22121366 NLM ISO Abbreviation: J Bone Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: CDK4/6 inhibitor ribociclib and doxorubicin combination treatment inhibits breast cancer bone metastasis and enhances T-cell targeted therapy.
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  Data: <searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Kobayashi+T%22">Kobayashi T</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Breast Medical Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Xiang+J%22">Xiang J</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Shajahan-Haq+AN%22">Shajahan-Haq AN</searchLink>; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.<br /><searchLink fieldCode="AU" term="%22Mardani+M%22">Mardani M</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Noordeen+S%22">Noordeen S</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22O'Donnell+K%22">O'Donnell K</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Kwakwa+KA%22">Kwakwa KA</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Guan+D%22">Guan D</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Fox+GC%22">Fox GC</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Fontana+F%22">Fontana F</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Cybulla+E%22">Cybulla E</searchLink>; Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210, USA.<br /><searchLink fieldCode="AU" term="%22Bakewell+S%22">Bakewell S</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Vindigni+A%22">Vindigni A</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Veis+DJ%22">Veis DJ</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Musculoskeletal Research Center, Histology and Morphometry Core, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Achilefu+S%22">Achilefu S</searchLink>; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, TX 7530, USA.<br /><searchLink fieldCode="AU" term="%22Lanza+GM%22">Lanza GM</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Weilbaecher+KN%22">Weilbaecher KN</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
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  Data: <searchLink fieldCode="JN" term="%22101610292%22">Journal of bone oncology</searchLink> [J Bone Oncol] 2026 Apr 25; Vol. 58, pp. 100765. <i>Date of Electronic Publication: </i>2026 Apr 25 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101610292 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2212-1366 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222121366%22">22121366 </searchLink><i>NLM ISO Abbreviation: </i>J Bone Oncol <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42095207
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        Value: 10.1016/j.jbo.2026.100765
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              Text: 2026 Apr 25
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