Impact of cardiometabolic comorbidities on clinical characteristics, prescription patterns and retention rate of first b/tsDMARD treatment in 5299 European real-world patients with psoriatic arthritis.

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Title: Impact of cardiometabolic comorbidities on clinical characteristics, prescription patterns and retention rate of first b/tsDMARD treatment in 5299 European real-world patients with psoriatic arthritis.
Authors: Ahmadzay ZF; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark zohra.faizy.ahmadzay@regionh.dk.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Ørnbjerg LM; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark., Østergaard M; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Jensen KY; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark., Jørgensen JB; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark., Heberg J; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark., Loft AG; Department of Rheumatology and DANBIO, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Michelsen B; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Research Unit, Sørlandet Hospital, Kristiansand, Norway., Jones GT; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK., Hellamand P; Department of Rheumatology and Clinical Immunology, Free University of Amsterdam, Amsterdam University Medical Centres, Amsterdam, The Netherlands.; Amsterdam UMC, Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, The Netherlands., Møller-Bisgaard S; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Reumaklinik Roskilde, Rheumatology Specialist Practice, Roskilde, Denmark., Shoae Kazemi M; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark., Karimi Reikandeh P; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; ParHub RnD ApS, Copenhagen, Denmark., Závada J; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, Charles University First Faculty of Medicine, Prague, Czech Republic., Horák P; Department of Internal Medicine-Nephrology, Rheumatology, Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic., Bernardes M; Department of Medicine, University of Porto Faculty of Medicine, Porto, Portugal.; Rheumatology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal., Vieira-Sousa E; Department of Rheumatology, ULSSM, Instituto Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Hospital de Santa Maria, Lisbon, Portugal., Castrejón I; Department of Rheumatology, Hospital General, Universitario Gregorio Marañón, Madrid, Spain.; Faculty of Medicine, Complutense University of Madrid, Madrid, Spain., Otero-Varela L; Research Unit, Spanish Society of Rheumatology, Madrid, Spain., Codreanu C; Centre for Rheumatic Disease, University of Medicine and Pharmacy, Bucharest, Romania., Kuusalo L; Department of Rheumatology, Division of Medicine, Turku University Hospital, Turku, Finland.; Department of Internal Medicine, University of Turku, Turku, Finland.; Rheumatology, Department of Medicine, Satakunta Central Hospital, Rauma, Finland., Rantalaiho V; Centre for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Medicine, Kanta-Häme Central Hospital, Hämeenlinna, Finland., Regierer AC; Epidemiology, German Rheumatology Research Center, Berlin, Germany., Reich A; Epidemiology, German Rheumatology Research Center, Berlin, Germany., Möller B; Department Rheumatology and Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Micheroli R; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Mielnik P; Section for Rheumatology, Department for Neurology, Rheumatology and Physical Medicine, Helse Førde, Forde, Norway., Provan SA; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Public Health Section, University of Inland Norway, Elverum, Norway., Lass K; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Vorobjov S; Section for Rheumatology, Department for Neurology, Rheumatology and Physical Medicine, Helse Førde, Forde, Norway., Rotar Z; Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Pirkmajer KP; Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Iannone F; Rheumatology Unit-Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy., Conti F; Rheumatology, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza, University of Rome, Rome, Italy., Gudbjornsson B; Centre for Rheumatology Research, Landspítali-The National University Hospital of Iceland, Reykjavík, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Di Giuseppe D; Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden., van de Sande M; Department of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam Institute for Immunology & Infectious Diseases, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Rheumatology and Immunology Center, Reade and Amsterdam UMC, Amsterdam, The Netherlands., Macfarlane GJ; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK., Yarkan-Tuğsal H; Department of Internal Medicine, Division of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey., Glintborg B; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Hetland ML; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Source: RMD open [RMD Open] 2026 May 07; Vol. 12 (2). Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101662038 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-5933 (Electronic) Linking ISSN: 20565933 NLM ISO Abbreviation: RMD Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of cardiometabolic comorbidities on clinical characteristics, prescription patterns and retention rate of first b/tsDMARD treatment in 5299 European real-world patients with psoriatic arthritis.
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  Data: <searchLink fieldCode="AU" term="%22Ahmadzay+ZF%22">Ahmadzay ZF</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark zohra.faizy.ahmadzay@regionh.dk.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ørnbjerg+LM%22">Ørnbjerg LM</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Østergaard+M%22">Østergaard M</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+KY%22">Jensen KY</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Jørgensen+JB%22">Jørgensen JB</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Heberg+J%22">Heberg J</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Loft+AG%22">Loft AG</searchLink>; Department of Rheumatology and DANBIO, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Michelsen+B%22">Michelsen B</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Research Unit, Sørlandet Hospital, Kristiansand, Norway.<br /><searchLink fieldCode="AU" term="%22Jones+GT%22">Jones GT</searchLink>; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK.<br /><searchLink fieldCode="AU" term="%22Hellamand+P%22">Hellamand P</searchLink>; Department of Rheumatology and Clinical Immunology, Free University of Amsterdam, Amsterdam University Medical Centres, Amsterdam, The Netherlands.; Amsterdam UMC, Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Møller-Bisgaard+S%22">Møller-Bisgaard S</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Reumaklinik Roskilde, Rheumatology Specialist Practice, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Shoae+Kazemi+M%22">Shoae Kazemi M</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Karimi+Reikandeh+P%22">Karimi Reikandeh P</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; ParHub RnD ApS, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Závada+J%22">Závada J</searchLink>; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, Charles University First Faculty of Medicine, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Horák+P%22">Horák P</searchLink>; Department of Internal Medicine-Nephrology, Rheumatology, Endocrinology, University Hospital Olomouc, Olomouc, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bernardes+M%22">Bernardes M</searchLink>; Department of Medicine, University of Porto Faculty of Medicine, Porto, Portugal.; Rheumatology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Vieira-Sousa+E%22">Vieira-Sousa E</searchLink>; Department of Rheumatology, ULSSM, Instituto Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Hospital de Santa Maria, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Castrejón+I%22">Castrejón I</searchLink>; Department of Rheumatology, Hospital General, Universitario Gregorio Marañón, Madrid, Spain.; Faculty of Medicine, Complutense University of Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Otero-Varela+L%22">Otero-Varela L</searchLink>; Research Unit, Spanish Society of Rheumatology, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Codreanu+C%22">Codreanu C</searchLink>; Centre for Rheumatic Disease, University of Medicine and Pharmacy, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Kuusalo+L%22">Kuusalo L</searchLink>; Department of Rheumatology, Division of Medicine, Turku University Hospital, Turku, Finland.; Department of Internal Medicine, University of Turku, Turku, Finland.; Rheumatology, Department of Medicine, Satakunta Central Hospital, Rauma, Finland.<br /><searchLink fieldCode="AU" term="%22Rantalaiho+V%22">Rantalaiho V</searchLink>; Centre for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Medicine, Kanta-Häme Central Hospital, Hämeenlinna, Finland.<br /><searchLink fieldCode="AU" term="%22Regierer+AC%22">Regierer AC</searchLink>; Epidemiology, German Rheumatology Research Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Reich+A%22">Reich A</searchLink>; Epidemiology, German Rheumatology Research Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Möller+B%22">Möller B</searchLink>; Department Rheumatology and Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Micheroli+R%22">Micheroli R</searchLink>; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mielnik+P%22">Mielnik P</searchLink>; Section for Rheumatology, Department for Neurology, Rheumatology and Physical Medicine, Helse Førde, Forde, Norway.<br /><searchLink fieldCode="AU" term="%22Provan+SA%22">Provan SA</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Public Health Section, University of Inland Norway, Elverum, Norway.<br /><searchLink fieldCode="AU" term="%22Lass+K%22">Lass K</searchLink>; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vorobjov+S%22">Vorobjov S</searchLink>; Section for Rheumatology, Department for Neurology, Rheumatology and Physical Medicine, Helse Førde, Forde, Norway.<br /><searchLink fieldCode="AU" term="%22Rotar+Z%22">Rotar Z</searchLink>; Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Pirkmajer+KP%22">Pirkmajer KP</searchLink>; Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Iannone+F%22">Iannone F</searchLink>; Rheumatology Unit-Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Conti+F%22">Conti F</searchLink>; Rheumatology, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza, University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gudbjornsson+B%22">Gudbjornsson B</searchLink>; Centre for Rheumatology Research, Landspítali-The National University Hospital of Iceland, Reykjavík, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Di+Giuseppe+D%22">Di Giuseppe D</searchLink>; Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22van+de+Sande+M%22">van de Sande M</searchLink>; Department of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam Institute for Immunology & Infectious Diseases, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Rheumatology and Immunology Center, Reade and Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Macfarlane+GJ%22">Macfarlane GJ</searchLink>; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK.<br /><searchLink fieldCode="AU" term="%22Yarkan-Tuğsal+H%22">Yarkan-Tuğsal H</searchLink>; Department of Internal Medicine, Division of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Glintborg+B%22">Glintborg B</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hetland+ML%22">Hetland ML</searchLink>; Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet Center for Rheumatology and Spine Diseases, Glostrup, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
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