Intravenous Tirofiban After Tenecteplase in Acute Ischemic Stroke: The INSTANT Randomized Clinical Trial.

Saved in:
Bibliographic Details
Title: Intravenous Tirofiban After Tenecteplase in Acute Ischemic Stroke: The INSTANT Randomized Clinical Trial.
Authors: Liu X; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Zhang F; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Zhang C; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Li Z; Department of Neurology, Mingguang People's Hospital, Chuzhou, China., Yuan G; Department of Emergency, Xiangtan Central Hospital (The Affiliated Hospital of Hunan University), Xiangtan, China., Kong D; Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Xie S; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Zhou M; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Ye J; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Lai Z; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Li D; Department of Neurology, Zhongmeng Hospital of Hexigten Banner, Chifeng, China., Xu H; Department of Neurology, Yiling People's Hospital of Yichang City, Yichang, China., Chen L; Department of Neurology, Mingguang People's Hospital, Chuzhou, China., Cheng F; Department of Emergency, Xiangtan Central Hospital (The Affiliated Hospital of Hunan University), Xiangtan, China., Shi Y; Department of Neurology, People's Hospital of Xinfeng County, Xinfeng, China., Chen B; Department of Neurology, People's Hospital of Quannan County, Quannan, China., Hu W; Department of Neurology, People's Hospital of Ganxian District, Ganzhou, China., Liu H; Department of Neurology, People's Hospital of Dayu County, Dayu, China., Yin Y; Department of Neurology, People's Hospital of Shangyou County, Shangyou, China., Deng X; Department of Neurology, People's Hospital of Yichun, Yichun, China., Xie Z; Department of Neurology, People's Hospital of Yudu County, Yudu, China., Li C; Department of Neurology, Songyuan Jilin Oilfield Hospital, Songyuan, China., Shi J; Department of Neurology, Huangmei People's Hospital, Huangmei, China., Mei D; Department of Neurology, People's Hospital of Xunwu County, Xunwu, China., Liu B; Department of Neurology, People's Hospital of Wan'an County, Wan'an, China., Wang B; Department of Neurology, Hunan Xupu Chengnan Hospital, Huaihua, China., Zhou R; Department of Neurology, People's Hospital of Ruijin City, Ruijin, China., Liu J; Department of Neurology, Yingtan People's Hospital, Yingtan, China., Shen L; Department of Neurology, People's Hospital of Shaodong, Shaodong, China., Hu H; Department of Neurology, People's Hospital of Ningdu County, Ningdu, China., Xiao G; Department of Neurology, People's Hospital of Shicheng County, Shicheng, China., Guan X; Department of Neurology, Second People's Hospital of Yudu County, Yudu, China., Yuan S; Department of Neurology, Second Hospital of Xingguo County, Xingguo, China., Lv X; Department of Neurology, People's Hospital of Chongyi County, Chongyi, China., Liang S; Department of Neurology, Traditional Chinese Medicine Hospital of Xingguo County, Xingguo, China., Zeng X; Department of Neurology, Hunan University of Medicine Affiliated Pingjiang Hospital (Pingjiang County First People's Hospital), Pingjiang, China., Chen Y; Department of Neurology, Ji'an Central People's Hospital, Ji'an, China., Cao W; Department of Neurology, Jiangxi Provincial People's Hospital, Nanchang, China., Zheng C; Department of Neurology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China., Liu Y; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Li J; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Guan B; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Lai T; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Sun W; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Zeng H; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China., Zhang J; Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Li S; Department of Neurology, First People's Hospital of Yulin, Yulin, China., Sang H; Department of Neurology, Hangzhou First People's Hospital and School of Medicine of Westlake University, Hangzhou, China., Tang Y; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China., Wang D; Global Health Trials Unit, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Lu M; Health Science Center, Ningbo University, Ningbo, China., Kaesmacher J; University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland., Yogendrakumar V; Division of Neurology, Ottawa Hospital and the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.; Department of Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia., Pan S; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Nogueira RG; UPMC Stroke Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Hong D; Department of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China., Goyal M; Departments of Radiology and Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada., Thomalla G; Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Nguyen TN; Department of Neurology, Boston Medical Center, Boston., Saver JL; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles., Yang Q; Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China., Qiu Z; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China., Zeng G; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.
Corporate Authors: INSTANT Trial Authors for the INSTANT Investigators
Source: JAMA [JAMA] 2026 Jun 09; Vol. 335 (22), pp. 1949-1958.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42100960
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Intravenous Tirofiban After Tenecteplase in Acute Ischemic Stroke: The INSTANT Randomized Clinical Trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Neurology, Mingguang People's Hospital, Chuzhou, China.<br /><searchLink fieldCode="AU" term="%22Yuan+G%22">Yuan G</searchLink>; Department of Emergency, Xiangtan Central Hospital (The Affiliated Hospital of Hunan University), Xiangtan, China.<br /><searchLink fieldCode="AU" term="%22Kong+D%22">Kong D</searchLink>; Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Xie+S%22">Xie S</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+M%22">Zhou M</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Ye+J%22">Ye J</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Lai+Z%22">Lai Z</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Department of Neurology, Zhongmeng Hospital of Hexigten Banner, Chifeng, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Neurology, Yiling People's Hospital of Yichang City, Yichang, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Neurology, Mingguang People's Hospital, Chuzhou, China.<br /><searchLink fieldCode="AU" term="%22Cheng+F%22">Cheng F</searchLink>; Department of Emergency, Xiangtan Central Hospital (The Affiliated Hospital of Hunan University), Xiangtan, China.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Department of Neurology, People's Hospital of Xinfeng County, Xinfeng, China.<br /><searchLink fieldCode="AU" term="%22Chen+B%22">Chen B</searchLink>; Department of Neurology, People's Hospital of Quannan County, Quannan, China.<br /><searchLink fieldCode="AU" term="%22Hu+W%22">Hu W</searchLink>; Department of Neurology, People's Hospital of Ganxian District, Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Neurology, People's Hospital of Dayu County, Dayu, China.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Department of Neurology, People's Hospital of Shangyou County, Shangyou, China.<br /><searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; Department of Neurology, People's Hospital of Yichun, Yichun, China.<br /><searchLink fieldCode="AU" term="%22Xie+Z%22">Xie Z</searchLink>; Department of Neurology, People's Hospital of Yudu County, Yudu, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Neurology, Songyuan Jilin Oilfield Hospital, Songyuan, China.<br /><searchLink fieldCode="AU" term="%22Shi+J%22">Shi J</searchLink>; Department of Neurology, Huangmei People's Hospital, Huangmei, China.<br /><searchLink fieldCode="AU" term="%22Mei+D%22">Mei D</searchLink>; Department of Neurology, People's Hospital of Xunwu County, Xunwu, China.<br /><searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; Department of Neurology, People's Hospital of Wan'an County, Wan'an, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Department of Neurology, Hunan Xupu Chengnan Hospital, Huaihua, China.<br /><searchLink fieldCode="AU" term="%22Zhou+R%22">Zhou R</searchLink>; Department of Neurology, People's Hospital of Ruijin City, Ruijin, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Neurology, Yingtan People's Hospital, Yingtan, China.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Department of Neurology, People's Hospital of Shaodong, Shaodong, China.<br /><searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; Department of Neurology, People's Hospital of Ningdu County, Ningdu, China.<br /><searchLink fieldCode="AU" term="%22Xiao+G%22">Xiao G</searchLink>; Department of Neurology, People's Hospital of Shicheng County, Shicheng, China.<br /><searchLink fieldCode="AU" term="%22Guan+X%22">Guan X</searchLink>; Department of Neurology, Second People's Hospital of Yudu County, Yudu, China.<br /><searchLink fieldCode="AU" term="%22Yuan+S%22">Yuan S</searchLink>; Department of Neurology, Second Hospital of Xingguo County, Xingguo, China.<br /><searchLink fieldCode="AU" term="%22Lv+X%22">Lv X</searchLink>; Department of Neurology, People's Hospital of Chongyi County, Chongyi, China.<br /><searchLink fieldCode="AU" term="%22Liang+S%22">Liang S</searchLink>; Department of Neurology, Traditional Chinese Medicine Hospital of Xingguo County, Xingguo, China.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Department of Neurology, Hunan University of Medicine Affiliated Pingjiang Hospital (Pingjiang County First People's Hospital), Pingjiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Neurology, Ji'an Central People's Hospital, Ji'an, China.<br /><searchLink fieldCode="AU" term="%22Cao+W%22">Cao W</searchLink>; Department of Neurology, Jiangxi Provincial People's Hospital, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+C%22">Zheng C</searchLink>; Department of Neurology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Guan+B%22">Guan B</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Lai+T%22">Lai T</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Sun+W%22">Sun W</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zeng+H%22">Zeng H</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Neurology, First People's Hospital of Yulin, Yulin, China.<br /><searchLink fieldCode="AU" term="%22Sang+H%22">Sang H</searchLink>; Department of Neurology, Hangzhou First People's Hospital and School of Medicine of Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Global Health Trials Unit, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lu+M%22">Lu M</searchLink>; Health Science Center, Ningbo University, Ningbo, China.<br /><searchLink fieldCode="AU" term="%22Kaesmacher+J%22">Kaesmacher J</searchLink>; University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yogendrakumar+V%22">Yogendrakumar V</searchLink>; Division of Neurology, Ottawa Hospital and the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.; Department of Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pan+S%22">Pan S</searchLink>; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Nogueira+RG%22">Nogueira RG</searchLink>; UPMC Stroke Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hong+D%22">Hong D</searchLink>; Department of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Goyal+M%22">Goyal M</searchLink>; Departments of Radiology and Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Thomalla+G%22">Thomalla G</searchLink>; Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nguyen+TN%22">Nguyen TN</searchLink>; Department of Neurology, Boston Medical Center, Boston.<br /><searchLink fieldCode="AU" term="%22Saver+JL%22">Saver JL</searchLink>; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Qiu+Z%22">Qiu Z</searchLink>; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zeng+G%22">Zeng G</searchLink>; Department of Neurology, The Affiliated Ganzhou Hospital of Nanchang University (Ganzhou People's Hospital), Ganzhou, China.; Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, China.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22INSTANT+Trial+Authors+for+the+INSTANT+Investigators%22">INSTANT Trial Authors for the INSTANT Investigators</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2026 Jun 09; Vol. 335 (22), pp. 1949-1958.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7501160 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-3598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200987484%22">00987484 </searchLink><i>NLM ISO Abbreviation: </i>JAMA <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42100960
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1001/jama.2026.5245
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1949
    Titles:
      – TitleFull: Intravenous Tirofiban After Tenecteplase in Acute Ischemic Stroke: The INSTANT Randomized Clinical Trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Liu X
      – PersonEntity:
          Name:
            NameFull: Zhang F
      – PersonEntity:
          Name:
            NameFull: Zhang C
      – PersonEntity:
          Name:
            NameFull: Li Z
      – PersonEntity:
          Name:
            NameFull: Yuan G
      – PersonEntity:
          Name:
            NameFull: Kong D
      – PersonEntity:
          Name:
            NameFull: Xie S
      – PersonEntity:
          Name:
            NameFull: Zhou M
      – PersonEntity:
          Name:
            NameFull: Ye J
      – PersonEntity:
          Name:
            NameFull: Lai Z
      – PersonEntity:
          Name:
            NameFull: Li D
      – PersonEntity:
          Name:
            NameFull: Xu H
      – PersonEntity:
          Name:
            NameFull: Chen L
      – PersonEntity:
          Name:
            NameFull: Cheng F
      – PersonEntity:
          Name:
            NameFull: Shi Y
      – PersonEntity:
          Name:
            NameFull: Chen B
      – PersonEntity:
          Name:
            NameFull: Hu W
      – PersonEntity:
          Name:
            NameFull: Liu H
      – PersonEntity:
          Name:
            NameFull: Yin Y
      – PersonEntity:
          Name:
            NameFull: Deng X
      – PersonEntity:
          Name:
            NameFull: Xie Z
      – PersonEntity:
          Name:
            NameFull: Li C
      – PersonEntity:
          Name:
            NameFull: Shi J
      – PersonEntity:
          Name:
            NameFull: Mei D
      – PersonEntity:
          Name:
            NameFull: Liu B
      – PersonEntity:
          Name:
            NameFull: Wang B
      – PersonEntity:
          Name:
            NameFull: Zhou R
      – PersonEntity:
          Name:
            NameFull: Liu J
      – PersonEntity:
          Name:
            NameFull: Shen L
      – PersonEntity:
          Name:
            NameFull: Hu H
      – PersonEntity:
          Name:
            NameFull: Xiao G
      – PersonEntity:
          Name:
            NameFull: Guan X
      – PersonEntity:
          Name:
            NameFull: Yuan S
      – PersonEntity:
          Name:
            NameFull: Lv X
      – PersonEntity:
          Name:
            NameFull: Liang S
      – PersonEntity:
          Name:
            NameFull: Zeng X
      – PersonEntity:
          Name:
            NameFull: Chen Y
      – PersonEntity:
          Name:
            NameFull: Cao W
      – PersonEntity:
          Name:
            NameFull: Zheng C
      – PersonEntity:
          Name:
            NameFull: Liu Y
      – PersonEntity:
          Name:
            NameFull: Li J
      – PersonEntity:
          Name:
            NameFull: Guan B
      – PersonEntity:
          Name:
            NameFull: Lai T
      – PersonEntity:
          Name:
            NameFull: Sun W
      – PersonEntity:
          Name:
            NameFull: Zeng H
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Li S
      – PersonEntity:
          Name:
            NameFull: Sang H
      – PersonEntity:
          Name:
            NameFull: Tang Y
      – PersonEntity:
          Name:
            NameFull: Wang D
      – PersonEntity:
          Name:
            NameFull: Lu M
      – PersonEntity:
          Name:
            NameFull: Kaesmacher J
      – PersonEntity:
          Name:
            NameFull: Yogendrakumar V
      – PersonEntity:
          Name:
            NameFull: Pan S
      – PersonEntity:
          Name:
            NameFull: Nogueira RG
      – PersonEntity:
          Name:
            NameFull: Hong D
      – PersonEntity:
          Name:
            NameFull: Goyal M
      – PersonEntity:
          Name:
            NameFull: Thomalla G
      – PersonEntity:
          Name:
            NameFull: Nguyen TN
      – PersonEntity:
          Name:
            NameFull: Saver JL
      – PersonEntity:
          Name:
            NameFull: Yang Q
      – PersonEntity:
          Name:
            NameFull: Qiu Z
      – PersonEntity:
          Name:
            NameFull: Zeng G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 09
              M: 06
              Text: 2026 Jun 09
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1538-3598
          Numbering:
            – Type: volume
              Value: 335
            – Type: issue
              Value: 22
          Titles:
            – TitleFull: JAMA
              Type: main
ResultId 1