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D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes.

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Title: D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes.
Authors: Kearns FL; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340., Bogetti AT; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260., Calvó-Tusell C; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340., Braza MKE; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0340., Casalino L; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340., Gramm AJ; Department of Chemistry, Pennsylvania State University, University Park, PA 16802., Braet S; Department of Chemistry, Pennsylvania State University, University Park, PA 16802., Rosenfeld MA; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340., Rajapaksha H; Oracle for Research, Oracle Cloud, Austin, TX 78741., Barker B; Oracle for Research, Oracle Cloud, Austin, TX 78741., Anand G; Department of Chemistry, Pennsylvania State University, University Park, PA 16802., Chong LT; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260., Ahn SH; Department of Chemical Engineering, University of California Davis, Davis, CA 95616., Amaro RE; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 12; Vol. 123 (19), pp. e2504793123. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes.
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  Data: <searchLink fieldCode="AU" term="%22Kearns+FL%22">Kearns FL</searchLink>; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.<br /><searchLink fieldCode="AU" term="%22Bogetti+AT%22">Bogetti AT</searchLink>; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260.<br /><searchLink fieldCode="AU" term="%22Calvó-Tusell+C%22">Calvó-Tusell C</searchLink>; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.<br /><searchLink fieldCode="AU" term="%22Braza+MKE%22">Braza MKE</searchLink>; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0340.<br /><searchLink fieldCode="AU" term="%22Casalino+L%22">Casalino L</searchLink>; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.<br /><searchLink fieldCode="AU" term="%22Gramm+AJ%22">Gramm AJ</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA 16802.<br /><searchLink fieldCode="AU" term="%22Braet+S%22">Braet S</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA 16802.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+MA%22">Rosenfeld MA</searchLink>; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.<br /><searchLink fieldCode="AU" term="%22Rajapaksha+H%22">Rajapaksha H</searchLink>; Oracle for Research, Oracle Cloud, Austin, TX 78741.<br /><searchLink fieldCode="AU" term="%22Barker+B%22">Barker B</searchLink>; Oracle for Research, Oracle Cloud, Austin, TX 78741.<br /><searchLink fieldCode="AU" term="%22Anand+G%22">Anand G</searchLink>; Department of Chemistry, Pennsylvania State University, University Park, PA 16802.<br /><searchLink fieldCode="AU" term="%22Chong+LT%22">Chong LT</searchLink>; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260.<br /><searchLink fieldCode="AU" term="%22Ahn+SH%22">Ahn SH</searchLink>; Department of Chemical Engineering, University of California Davis, Davis, CA 95616.<br /><searchLink fieldCode="AU" term="%22Amaro+RE%22">Amaro RE</searchLink>; Department of Molecular Biology, University of California San Diego, La Jolla, CA 92093-0340.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 May 12; Vol. 123 (19), pp. e2504793123. <i>Date of Electronic Publication: </i>2026 May 08.
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