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Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution.

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Bibliographic Details
Title: Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution.
Authors: Forsgren N; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Jonsson F; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Carlsson M; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Sander RA; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Larsson A; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Lindén P; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Linusson A; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden; Department of Chemistry, Umeå University, Umeå, Sweden., Engdahl CS; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Wiktelius D; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden., Ekström F; CBRN Defence and Security, Swedish Defence Research Agency, Umeå, Sweden. Electronic address: fredrik.ekstrom@foi.se.
Source: The Journal of biological chemistry [J Biol Chem] 2026 May 07; Vol. 302 (6), pp. 113115. Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2026.113115