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Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons.

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Title: Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons.
Authors: Gerónimo-Olvera C; Buck Institute for Research on Aging, Novato, California, USA., Scheeler SM; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Aguirre CG; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Vega-Hormazabal G; Buck Institute for Research on Aging, Novato, California, USA., Garcia D; Buck Institute for Research on Aging, Novato, California, USA., Wu L; Buck Institute for Research on Aging, Novato, California, USA., Murad N; Buck Institute for Research on Aging, Novato, California, USA., Schneider K; Buck Institute for Research on Aging, Novato, California, USA., Wilson KA; Buck Institute for Research on Aging, Novato, California, USA., Markov NT; Buck Institute for Research on Aging, Novato, California, USA., Song S; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA., Simons J; Buck Institute for Research on Aging, Novato, California, USA., Gerencser AA; Buck Institute for Research on Aging, Novato, California, USA., Parlan E; Buck Institute for Research on Aging, Novato, California, USA., Mooney SD; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA., Verdin E; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Campisi J; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Tracy TE; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Furman D; Buck Institute for Research on Aging, Novato, California, USA., Melov S; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA., Ellerby LM; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.
Source: Aging cell [Aging Cell] 2026 May; Vol. 25 (5), pp. e70494.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons.
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  Data: <searchLink fieldCode="AU" term="%22Gerónimo-Olvera+C%22">Gerónimo-Olvera C</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Scheeler+SM%22">Scheeler SM</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Aguirre+CG%22">Aguirre CG</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Vega-Hormazabal+G%22">Vega-Hormazabal G</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+D%22">Garcia D</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Murad+N%22">Murad N</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+K%22">Schneider K</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+KA%22">Wilson KA</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Markov+NT%22">Markov NT</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Song+S%22">Song S</searchLink>; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Simons+J%22">Simons J</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Gerencser+AA%22">Gerencser AA</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Parlan+E%22">Parlan E</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Mooney+SD%22">Mooney SD</searchLink>; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Verdin+E%22">Verdin E</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Campisi+J%22">Campisi J</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Tracy+TE%22">Tracy TE</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Furman+D%22">Furman D</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.<br /><searchLink fieldCode="AU" term="%22Melov+S%22">Melov S</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Ellerby+LM%22">Ellerby LM</searchLink>; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California, USA.
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