Cabozantinib and atezolizumab for recurrent or metastatic esophageal squamous cell carcinoma after platinum-based chemotherapy failure: a single-arm phase II study and biomarker analysis.

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Title: Cabozantinib and atezolizumab for recurrent or metastatic esophageal squamous cell carcinoma after platinum-based chemotherapy failure: a single-arm phase II study and biomarker analysis.
Authors: Kuo HY; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan., Huang TC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan., Chuang CH; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Wu TC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan., Huang YL; Department of Pathology, National Taiwan University Cancer Center, Taipei, Taiwan., Lin CC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Lee JM; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan., Guo JC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. jhecyuanguo@gmail.com.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. jhecyuanguo@gmail.com.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. jhecyuanguo@gmail.com., Hsu CH; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 May 09. Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cabozantinib and atezolizumab for recurrent or metastatic esophageal squamous cell carcinoma after platinum-based chemotherapy failure: a single-arm phase II study and biomarker analysis.
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  Data: <searchLink fieldCode="AU" term="%22Kuo+HY%22">Kuo HY</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+TC%22">Huang TC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuang+CH%22">Chuang CH</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+TC%22">Wu TC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YL%22">Huang YL</searchLink>; Department of Pathology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+JM%22">Lee JM</searchLink>; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Guo+JC%22">Guo JC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. jhecyuanguo@gmail.com.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. jhecyuanguo@gmail.com.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. jhecyuanguo@gmail.com.<br /><searchLink fieldCode="AU" term="%22Hsu+CH%22">Hsu CH</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2026 May 09. <i>Date of Electronic Publication: </i>2026 May 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00262-026-04408-w
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      – Code: eng
        Text: English
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      – TitleFull: Cabozantinib and atezolizumab for recurrent or metastatic esophageal squamous cell carcinoma after platinum-based chemotherapy failure: a single-arm phase II study and biomarker analysis.
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            – D: 09
              M: 05
              Text: 2026 May 09
              Type: published
              Y: 2026
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