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Stage-dependent changes in prostaglandin E₂ in tick saliva determine its immunosuppressive effects.

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Title: Stage-dependent changes in prostaglandin E₂ in tick saliva determine its immunosuppressive effects.
Authors: Nakamura H; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Parizi LF; Centro de Biotecnologia and Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Sajiki Y; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Okagawa T; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Business Development Unit, FASMAC Co., Ltd., Atsugi, Japan., Ikehata M; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Tiyamanee W; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Watari K; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Win SY; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Maekawa N; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Murata S; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan., Ohashi K; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan; International Affairs Office, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Logullo C; Laboratório de Bioquímica de Artrópodes Hematófagos, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., da Silva Vaz I Jr; Centro de Biotecnologia and Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: itabajara.vaz@ufrgs.br., Konnai S; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan; Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Japan; One Health Research Center, Hokkaido University, Sapporo, Japan. Electronic address: konnai@vetmed.hokudai.ac.jp.
Source: Ticks and tick-borne diseases [Ticks Tick Borne Dis] 2026 May; Vol. 17 (3), pp. 102654. Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101522599 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-9603 (Electronic) Linking ISSN: 1877959X NLM ISO Abbreviation: Ticks Tick Borne Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Stage-dependent changes in prostaglandin E₂ in tick saliva determine its immunosuppressive effects.
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  Data: <searchLink fieldCode="AU" term="%22Nakamura+H%22">Nakamura H</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Parizi+LF%22">Parizi LF</searchLink>; Centro de Biotecnologia and Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Sajiki+Y%22">Sajiki Y</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Okagawa+T%22">Okagawa T</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Business Development Unit, FASMAC Co., Ltd., Atsugi, Japan.<br /><searchLink fieldCode="AU" term="%22Ikehata+M%22">Ikehata M</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Tiyamanee+W%22">Tiyamanee W</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Watari+K%22">Watari K</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Win+SY%22">Win SY</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Maekawa+N%22">Maekawa N</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Murata+S%22">Murata S</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohashi+K%22">Ohashi K</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan; International Affairs Office, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Logullo+C%22">Logullo C</searchLink>; Laboratório de Bioquímica de Artrópodes Hematófagos, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+Vaz+I+Jr%22">da Silva Vaz I Jr</searchLink>; Centro de Biotecnologia and Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: itabajara.vaz@ufrgs.br.<br /><searchLink fieldCode="AU" term="%22Konnai+S%22">Konnai S</searchLink>; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan; Veterinary Research Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan; Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Japan; One Health Research Center, Hokkaido University, Sapporo, Japan. Electronic address: konnai@vetmed.hokudai.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101522599%22">Ticks and tick-borne diseases</searchLink> [Ticks Tick Borne Dis] 2026 May; Vol. 17 (3), pp. 102654. <i>Date of Electronic Publication: </i>2026 May 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101522599 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1877-9603 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221877959X%22">1877959X </searchLink><i>NLM ISO Abbreviation: </i>Ticks Tick Borne Dis <i>Subsets: </i>MEDLINE
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