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A decision tree model suggests a strong interaction effect between tumor size and a close surgical margin on the prognosis of limb salvage surgery in high-grade osteosarcoma.

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Title: A decision tree model suggests a strong interaction effect between tumor size and a close surgical margin on the prognosis of limb salvage surgery in high-grade osteosarcoma.
Authors: Shi Y; Department of Operating Room, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wei L; Department of Operating Room, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Nursing, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Bao Q; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Wen J; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Zhang Z; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Liu Z; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Liu Q; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Chen J; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Yang X; Department of Thoracic Surgery, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Source: Frontiers in surgery [Front Surg] 2026 Apr 24; Vol. 13, pp. 1801218. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101645127 Publication Model: eCollection Cited Medium: Print ISSN: 2296-875X (Print) Linking ISSN: 2296875X NLM ISO Abbreviation: Front Surg Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A decision tree model suggests a strong interaction effect between tumor size and a close surgical margin on the prognosis of limb salvage surgery in high-grade osteosarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Department of Operating Room, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wei+L%22">Wei L</searchLink>; Department of Operating Room, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Nursing, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bao+Q%22">Bao Q</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wen+J%22">Wen J</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Orthopedics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Thoracic Surgery, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%22101645127%22">Frontiers in surgery</searchLink> [Front Surg] 2026 Apr 24; Vol. 13, pp. 1801218. <i>Date of Electronic Publication: </i>2026 Apr 24 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2EA%22">Frontiers Media S.A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101645127 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2296-875X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222296875X%22">2296875X </searchLink><i>NLM ISO Abbreviation: </i>Front Surg <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42112485
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.3389/fsurg.2026.1801218
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      – Code: eng
        Text: English
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        StartPage: 1801218
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      – TitleFull: A decision tree model suggests a strong interaction effect between tumor size and a close surgical margin on the prognosis of limb salvage surgery in high-grade osteosarcoma.
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            – D: 24
              M: 04
              Text: 2026 Apr 24
              Type: published
              Y: 2026
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              Value: 13
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            – TitleFull: Frontiers in surgery
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