Premorbid adjustment problems, negative symptoms, and cognitive impairment in a large international sample at clinical high risk for psychosis: Findings from the Accelerating Medicines Partnership-Schizophrenia.
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| Title: | Premorbid adjustment problems, negative symptoms, and cognitive impairment in a large international sample at clinical high risk for psychosis: Findings from the Accelerating Medicines Partnership-Schizophrenia. |
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| Authors: | Cowan HR; Department of Psychology, Michigan State University, East Lansing, MI 44824, United States., Pratt D; Department of Psychology, Northwestern University, Evanston, IL 60208, United States., Shah JL; Douglas Research Centre, Montreal H4H 1R3, Canada., Woods SW; Departments of Psychiatry and Neuroscience, Yale University School of Medicine, New Haven, CT 06511, United States., Alameda L; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London WC2R 2LS, United Kingdom.; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program, Lausanne University Hospital (CHUV), Lausanne 1011, Switzerland.; Department of Psychiatry, Instituto de Investigación Sanitaria de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Sevilla 41013, Spain., Lepage M; Douglas Research Centre, Montreal H4H 1R3, Canada., Shankman SA; Department of Psychiatry, Northwestern University, Chicago, IL 60611, United States., Addington J; Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 4Z6, Canada., Arango C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, Instituto de Salud Carlos III, School of Medicine, Universidad Complutense, Madrid 28007, Spain., Bearden CE; Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, United States., Bouix S; Department of Software Engineering and Information Technology, École de Technologie Supérieure, Montréal, QC H3C 1K3, Canada., Breitborde NJK; Department of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States., Broome MR; Institute for Mental Health, University of Birmingham, Birmingham B15 2TT, United Kingdom., Cadenhead KS; Department of Psychiatry, University of California San Diego, San Diego, CA 92161, United States., Calkins ME; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States., Castillo-Passi RI; Department of Psychiatry, IMHAY, University of Chile, Santiago 843 1807, Chile., Chen EYH; LKS Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Choi J; Olin Neuropsychiatry Research Center, Hartford HealthCare Behavioral Health Network, Hartford, CT 06106, United States., Conus P; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London WC2R 2LS, United Kingdom.; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program, Lausanne University Hospital (CHUV), Lausanne 1011, Switzerland.; Department of Psychiatry, Instituto de Investigación Sanitaria de Sevilla, IBiS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Sevilla 41013, Spain., Corcoran CM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Cornblatt BA; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, United States., Diaz-Caneja CM; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, Instituto de Salud Carlos III, School of Medicine, Universidad Complutense, Madrid 28007, Spain., Ellman LM; Department of Psychology & Neuroscience, Temple University, Philadelphia, PA 19122, United States., Fusar-Poli P; Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, King's College London, London WC2R 2LS, United Kingdom.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.; Outreach and Support in South-London (OASIS) Service, South London and Maudlsey (SLaM) NHS Foundation Trust, London SE5 8AZ, United Kingdom.; Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University (LMU), Munich 80336, Germany., Gaspar PA; Department of Psychiatry, IMHAY, University of Chile, Santiago 843 1807, Chile., Gerber C; Prevention Science Institute, University of Oregon, Eugene, OR 97403, United States., Glenthøj LB; VIRTU Research Group, Copenhagen Research Centre for Mental Health, Mental Health Copenhagen, University of Copenhagen, Copenhagen 1850, Denmark., Gonçalves C; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC 3220, Australia., Horton LE; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States., Hui CLM; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Kambeitz J; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne 50937, Cologne, Germany., Kambeitz-Ilankovic L; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne 50937, Cologne, Germany., Kahn RS; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, United States., Kane JM; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, United States., Keshavan MS; Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States., Kim M; Department of Neuropsychiatry, Seoul National University Hospital, Seoul 13620, South Korea., Kim SW; Department of Psychiatry, Chonnam National University Medical School, Gwangju 61469, South Korea., Koutsouleris N; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, Munich 80539, Germany., Kwon JS; Department of Psychiatry, Hanyang University Hospital, Seoul 04763, South Korea., Langbein K; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena 07747, Germany., Mamah D; Department of Psychiatry, Washington University Medical School, St. Louis, MO 63110, United States., Mathalon DH; Department of Psychiatry and Behavioral Sciences and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., McGorry PD; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia.; Orygen, Parkville, VIC 3010, Australia., Nelson B; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia.; Orygen, Parkville, VIC 3010, Australia., Nordentoft M; Copenhagen Research Centre for Mental Health, Mental Health Copenhagen, University of Copenhagen, Hellerup 2900, Denmark., Pasternak O; Department of Psychiatry and Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States., Pearlson GD; Departments of Psychiatry and Neuroscience, Yale University School of Medicine, New Haven, CT 06511, United States., Perez J; CAMEO, Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge CB21 5EF, United Kingdom., Perkins DO; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, United States., Powers AR; Departments of Psychiatry and Neuroscience, Yale University School of Medicine, New Haven, CT 06511, United States., Rogers J; Institute for Mental Health, University of Birmingham, Birmingham B15 2TT, United Kingdom., Sabb FW; Prevention Science Institute, University of Oregon, Eugene, OR 97403, United States., Schiffman J; Department of Psychological Science, University of California, Irvine, Irvine, CA 92617, United States., Shenton ME; Department of Psychiatry and Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States., Silverstein SM; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, United States., Smesny S; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena 07747, Germany., Stone WS; Department of Psychiatry, Beth Israel Deaconess Medical Center, Massachusetts Mental Health Center, and Harvard Medical School, Boston, MA 02215, United States., Strauss GP; Department of Psychology, University of Georgia, Athens, GA 30602, United States., Thompson JL; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, United States., Upthegrove R; Institute for Mental Health, University of Birmingham, Birmingham B15 2TT, United Kingdom., Verma S; Institute of Mental Health, Singapore 539747, Singapore., Wang J; Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China., Wolf DH; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States., Yung A; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC 3220, Australia., Zhang T; Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China., Crawford C; Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States., Yassin W; Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States., Kelly S; Department of Psychiatry and Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States., Coleman M; Department of Psychiatry and Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States., Jacobs G; Department of Psychiatry and Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States., Lewandowski KE; Schizophrenia and Bipolar Disorder Program, McLean Hospital Department of Psychiatry, Harvard Medical School, Belmont, MA, 02478, United States., Penzel N; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston 02114, MA, United States., Baker J; Department of Psychiatry, McLean Hospital and Harvard Medical School, Boston, MA 02115, United States., Cecci G; IBM T.J. Watson Research Center, Yorktown Heights, NY 10598, United States., Allott K; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia., Buccilli K; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia., Tod S; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia., Addamo L; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia., Xu L; Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China., Mittal VA; Departments of Psychology and Medical Social Science, Northwestern University, Evanston, IL 60208, United States.; Department of Psychiatry, Northwestern University, Chicago, IL 60611, United States. |
| Corporate Authors: | Accelerating Medicines Partnership®—Schizophrenia (AMP® SCZ) |
| Source: | Schizophrenia bulletin [Schizophr Bull] 2025 Dec 05. Date of Electronic Publication: 2025 Dec 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0236760 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-1701 (Electronic) Linking ISSN: 05867614 NLM ISO Abbreviation: Schizophr Bull Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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