Therapeutic potential of mitochondrial transfer in reversing mutant-to-wild-type mtDNA ratio and improving mitochondrial dysfunction in 1555A>G mtDNA mutation-associated hearing loss.
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| Title: | Therapeutic potential of mitochondrial transfer in reversing mutant-to-wild-type mtDNA ratio and improving mitochondrial dysfunction in 1555A>G mtDNA mutation-associated hearing loss. |
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| Authors: | Kim Y; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Kim CH; Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea., Nam DW; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim BJ; Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Tran NT; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Han JH; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim M; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Yu SH; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Lee SE; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Yeo JS; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Kwon I; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Han K; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Kim CH; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea., Kang YC; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea. kangyc@paeanbio.com., Choi BY; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea. choiby2010@gmail.com.; Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Daejeon, Republic of Korea. choiby2010@gmail.com.; Sensory Organ Research Institute, Seoul National University Medical Research Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. choiby2010@gmail.com.; Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea. choiby2010@gmail.com.; Seoul National University Medical Research Center, College of Medicine, Seoul National University, Seoul, Korea. choiby2010@gmail.com. |
| Source: | Scientific reports [Sci Rep] 2026 May 13. Date of Electronic Publication: 2026 May 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42115265 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Therapeutic potential of mitochondrial transfer in reversing mutant-to-wild-type mtDNA ratio and improving mitochondrial dysfunction in 1555A>G mtDNA mutation-associated hearing loss. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CH%22">Kim CH</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+DW%22">Nam DW</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BJ%22">Kim BJ</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Tran+NT%22">Tran NT</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+JH%22">Han JH</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+SH%22">Yu SH</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SE%22">Lee SE</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yeo+JS%22">Yeo JS</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+I%22">Kwon I</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+K%22">Han K</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CH%22">Kim CH</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+YC%22">Kang YC</searchLink>; Paean Biotechnology, Inc. 5 Samil-daero8-gil, Jung-gu, Seoul, 04552, Republic of Korea. kangyc@paeanbio.com.<br /><searchLink fieldCode="AU" term="%22Choi+BY%22">Choi BY</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea. choiby2010@gmail.com.; Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Daejeon, Republic of Korea. choiby2010@gmail.com.; Sensory Organ Research Institute, Seoul National University Medical Research Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. choiby2010@gmail.com.; Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea. choiby2010@gmail.com.; Seoul National University Medical Research Center, College of Medicine, Seoul National University, Seoul, Korea. choiby2010@gmail.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 May 13. <i>Date of Electronic Publication: </i>2026 May 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42115265 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-51402-4 Languages: – Code: eng Text: English Titles: – TitleFull: Therapeutic potential of mitochondrial transfer in reversing mutant-to-wild-type mtDNA ratio and improving mitochondrial dysfunction in 1555A>G mtDNA mutation-associated hearing loss. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kim Y – PersonEntity: Name: NameFull: Kim CH – PersonEntity: Name: NameFull: Nam DW – PersonEntity: Name: NameFull: Kim BJ – PersonEntity: Name: NameFull: Tran NT – PersonEntity: Name: NameFull: Han JH – PersonEntity: Name: NameFull: Kim M – PersonEntity: Name: NameFull: Yu SH – PersonEntity: Name: NameFull: Lee SE – PersonEntity: Name: NameFull: Yeo JS – PersonEntity: Name: NameFull: Kwon I – PersonEntity: Name: NameFull: Han K – PersonEntity: Name: NameFull: Kim CH – PersonEntity: Name: NameFull: Kang YC – PersonEntity: Name: NameFull: Choi BY IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 05 Text: 2026 May 13 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Titles: – TitleFull: Scientific reports Type: main |
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