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The evolving global landscape of first-in-class oncology drug innovation.

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Title: The evolving global landscape of first-in-class oncology drug innovation.
Authors: Mao X; Vanke School of Public Health, Tsinghua University, Beijing, China.; Institute for Healthy China, Tsinghua University, Beijing, China., Wang Z; Vanke School of Public Health, Tsinghua University, Beijing, China.; Institute for Healthy China, Tsinghua University, Beijing, China., Kong S; School of Basic Medical Sciences, Tsinghua University, Beijing, China., Yang Y; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Key Laboratory of Innovative Drug Research and Evaluation, National Medical Products Administration, Beijing, China., Dreyer NA; University of North Carolina, Chapel Hill, NC, USA., Ba Y; Department of Oncology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China., Lotze MT; Departments of Surgery, Immunology and Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Zhan Q; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, China. zhanqimin@bjmu.edu.cn.; Peking University International Cancer Institute, Beijing, China. zhanqimin@bjmu.edu.cn., Li G; Vanke School of Public Health, Tsinghua University, Beijing, China. guanqiaoli@tsinghua.edu.cn.; Institute for Healthy China, Tsinghua University, Beijing, China. guanqiaoli@tsinghua.edu.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 May 11; Vol. 11 (1). Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The evolving global landscape of first-in-class oncology drug innovation.
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  Data: <searchLink fieldCode="AU" term="%22Mao+X%22">Mao X</searchLink>; Vanke School of Public Health, Tsinghua University, Beijing, China.; Institute for Healthy China, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Vanke School of Public Health, Tsinghua University, Beijing, China.; Institute for Healthy China, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Kong+S%22">Kong S</searchLink>; School of Basic Medical Sciences, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Key Laboratory of Innovative Drug Research and Evaluation, National Medical Products Administration, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Dreyer+NA%22">Dreyer NA</searchLink>; University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ba+Y%22">Ba Y</searchLink>; Department of Oncology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lotze+MT%22">Lotze MT</searchLink>; Departments of Surgery, Immunology and Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zhan+Q%22">Zhan Q</searchLink>; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, China. zhanqimin@bjmu.edu.cn.; Peking University International Cancer Institute, Beijing, China. zhanqimin@bjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Vanke School of Public Health, Tsinghua University, Beijing, China. guanqiaoli@tsinghua.edu.cn.; Institute for Healthy China, Tsinghua University, Beijing, China. guanqiaoli@tsinghua.edu.cn.
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        Value: 10.1038/s41392-026-02606-7
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              Text: 2026 May 11
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