TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens.
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| Title: | TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens. |
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| Authors: | Sekar A; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Selvadurai BR; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Chatterjee R; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Pal L; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Verma A; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Belugali Nataraj N; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; Bugworks Research Inc, C-CAMP, NCBS Campus, Bangalore, India., Drago Garcia D; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; The Francis Crick Institute, London, UK., Giri S; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Genna A; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Karatekin F; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; National University of Singapore, Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore., Gupta N; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Ramesh-Kumar D; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Zerbib M; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Vinik Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Avioz T; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Weizman E; Department of Genomics Unit, Weizmann Institute of Science, Rehovot, Israel., David E; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Schäffer AA; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Pan Y; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., Huang H; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., van Weerden WM; Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands., Corey E; Department of Urology, University of Washington School of Medicine, Seattle, WA, USA., Hunt H; Corcept Therapeutics, Menlo Park, CA, USA., Greenstein AE; Exelixis, Inc., 1851 Harbor Bay Pkwy, Alameda, CA, USA., Blecher-Gonen R; Department of Genomics Unit, Weizmann Institute of Science, Rehovot, Israel., Oren R; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Afek A; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Amit I; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Lev S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Ku A; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kartal S; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., R Bright J; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., T Lis R; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., L Dahut W; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Sowalsky AG; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ruppin E; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yarden Y; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel. yosef.yarden@weizmann.ac.il. |
| Source: | EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2062-2097. Date of Electronic Publication: 2026 May 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42120493 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sekar+A%22">Sekar A</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Selvadurai+BR%22">Selvadurai BR</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Chatterjee+R%22">Chatterjee R</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Pal+L%22">Pal L</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Verma+A%22">Verma A</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Belugali+Nataraj+N%22">Belugali Nataraj N</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; Bugworks Research Inc, C-CAMP, NCBS Campus, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Drago+Garcia+D%22">Drago Garcia D</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Giri+S%22">Giri S</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Genna+A%22">Genna A</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Karatekin+F%22">Karatekin F</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.; National University of Singapore, Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Gupta+N%22">Gupta N</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Ramesh-Kumar+D%22">Ramesh-Kumar D</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Zerbib+M%22">Zerbib M</searchLink>; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Vinik+Y%22">Vinik Y</searchLink>; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Avioz+T%22">Avioz T</searchLink>; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Weizman+E%22">Weizman E</searchLink>; Department of Genomics Unit, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22David+E%22">David E</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Schäffer+AA%22">Schäffer AA</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pan+Y%22">Pan Y</searchLink>; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Huang+H%22">Huang H</searchLink>; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22van+Weerden+WM%22">van Weerden WM</searchLink>; Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Corey+E%22">Corey E</searchLink>; Department of Urology, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hunt+H%22">Hunt H</searchLink>; Corcept Therapeutics, Menlo Park, CA, USA.<br /><searchLink fieldCode="AU" term="%22Greenstein+AE%22">Greenstein AE</searchLink>; Exelixis, Inc., 1851 Harbor Bay Pkwy, Alameda, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blecher-Gonen+R%22">Blecher-Gonen R</searchLink>; Department of Genomics Unit, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Oren+R%22">Oren R</searchLink>; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Afek+A%22">Afek A</searchLink>; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Amit+I%22">Amit I</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Lev+S%22">Lev S</searchLink>; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Ku+A%22">Ku A</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kartal+S%22">Kartal S</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22R+Bright+J%22">R Bright J</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22T+Lis+R%22">T Lis R</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22L+Dahut+W%22">L Dahut W</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sowalsky+AG%22">Sowalsky AG</searchLink>; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ruppin+E%22">Ruppin E</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yarden+Y%22">Yarden Y</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel. yosef.yarden@weizmann.ac.il. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2062-2097. <i>Date of Electronic Publication: </i>2026 May 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42120493 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s44321-026-00423-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2062 Titles: – TitleFull: TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sekar A – PersonEntity: Name: NameFull: Selvadurai BR – PersonEntity: Name: NameFull: Chatterjee R – PersonEntity: Name: NameFull: Pal L – PersonEntity: Name: NameFull: Verma A – PersonEntity: Name: NameFull: Belugali Nataraj N – PersonEntity: Name: NameFull: Drago Garcia D – PersonEntity: Name: NameFull: Giri S – PersonEntity: Name: NameFull: Genna A – PersonEntity: Name: NameFull: Karatekin F – PersonEntity: Name: NameFull: Gupta N – PersonEntity: Name: NameFull: Ramesh-Kumar D – PersonEntity: Name: NameFull: Zerbib M – PersonEntity: Name: NameFull: Vinik Y – PersonEntity: Name: NameFull: Avioz T – PersonEntity: Name: NameFull: Weizman E – PersonEntity: Name: NameFull: David E – PersonEntity: Name: NameFull: Schäffer AA – PersonEntity: Name: NameFull: Pan Y – PersonEntity: Name: NameFull: Huang H – PersonEntity: Name: NameFull: van Weerden WM – PersonEntity: Name: NameFull: Corey E – PersonEntity: Name: NameFull: Hunt H – PersonEntity: Name: NameFull: Greenstein AE – PersonEntity: Name: NameFull: Blecher-Gonen R – PersonEntity: Name: NameFull: Oren R – PersonEntity: Name: NameFull: Afek A – PersonEntity: Name: NameFull: Amit I – PersonEntity: Name: NameFull: Lev S – PersonEntity: Name: NameFull: Ku A – PersonEntity: Name: NameFull: Kartal S – PersonEntity: Name: NameFull: R Bright J – PersonEntity: Name: NameFull: T Lis R – PersonEntity: Name: NameFull: L Dahut W – PersonEntity: Name: NameFull: Sowalsky AG – PersonEntity: Name: NameFull: Ruppin E – PersonEntity: Name: NameFull: Yarden Y IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1757-4684 Numbering: – Type: volume Value: 18 – Type: issue Value: 6 Titles: – TitleFull: EMBO molecular medicine Type: main |
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