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5-(Benzofuran-2-yl)-3-(2-chloro-4-fluorobenzyl)-1,3,4-oxadiazol-2(3H)-one (GM-90663) Alleviates Dravet Syndrome via Inhibiting Monoamine Oxidase Activity.

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Title: 5-(Benzofuran-2-yl)-3-(2-chloro-4-fluorobenzyl)-1,3,4-oxadiazol-2(3H)-one (GM-90663) Alleviates Dravet Syndrome via Inhibiting Monoamine Oxidase Activity.
Authors: Hwang KS; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Ahn SH; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Son Y; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Kim SS; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Shin DS; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Yang JY; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Chae CH; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea., Nakamura M; Department of Pharmacology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of Korea.; Brain Science & Engineering Institute, Kyungpook National University, Daegu 41940, Republic of Korea., Jang IS; Department of Pharmacology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of Korea.; Brain Science & Engineering Institute, Kyungpook National University, Daegu 41940, Republic of Korea., Kim G; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.; Department of Medical Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Republic of Korea., Kim DG; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Kim P; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Heo Y; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Bae S; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Lee H; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea., Ahn JH; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.; JD Bioscience Inc., 208 Cheomdan-dwagiro, Buk-gu, Gwangju 61011, Republic of Korea., Bae MA; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.; Department of Medical Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Republic of Korea.
Source: Molecules (Basel, Switzerland) [Molecules] 2026 May 01; Vol. 31 (9). Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
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  Data: 5-(Benzofuran-2-yl)-3-(2-chloro-4-fluorobenzyl)-1,3,4-oxadiazol-2(3H)-one (GM-90663) Alleviates Dravet Syndrome via Inhibiting Monoamine Oxidase Activity.
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