Optogenetic WNT signaling drives germ layer self-organization in a human gastruloid model.
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| Title: | Optogenetic WNT signaling drives germ layer self-organization in a human gastruloid model. |
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| Authors: | Johnson HJ; Department of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.; Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley; Berkeley, California, 94720, USA., McMullin DM; Department of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.; Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley; Berkeley, California, 94720, USA.; Center for Computational Biology, University of California, Berkeley; Berkeley California, 94720., Zimmermann JA; Department of Chemical and Biomolecular Engineering, University of California, Berkeley; Berkeley, California, 94720, USA., Kim CN; Department of Anatomy, University of California, San Francisco; San Francisco, CA, 94158, USA.; Department of Psychiatry, University of California, San Francisco; San Francisco, CA, 94158, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco; San Francisco, CA, 94158, USA., Repina NA; Department of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.; Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley; Berkeley, California, 94720, USA., Bhalerao R; Department of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA., Nowakowski TJ; Department of Anatomy, University of California, San Francisco; San Francisco, CA, 94158, USA.; Department of Psychiatry, University of California, San Francisco; San Francisco, CA, 94158, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco; San Francisco, CA, 94158, USA., Schaffer DV; Department of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.; Department of Chemical and Biomolecular Engineering, University of California, Berkeley; Berkeley, California, 94720, USA.; Helen Wills Neuroscience Institute, University of California, Berkeley; Berkeley, California, 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley; Berkeley, California, 94720, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 25. Date of Electronic Publication: 2026 Feb 25. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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