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Maresin 1 induces resolution of hepatic fibrosis through RORα-dependent reprogramming of resident macrophages.

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Title: Maresin 1 induces resolution of hepatic fibrosis through RORα-dependent reprogramming of resident macrophages.
Authors: Herrera Vielma F; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Institute of Chemistry of Natural Resources, University of Talca, Talca, Chile., Quiñones San Martin M; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Institute of Chemistry of Natural Resources, University of Talca, Talca, Chile., Muñoz-Carrasco N; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; School of Biotechnology Engineering, Faculty of Agricultural and Forestry Sciences, Catholic University of Maule, Talca, Chile., Berrocal-Navarrete F; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Faculty of Health Sciences, University of Talca, Talca, Chile., Herrada AA; Lymphatic Vasculature and Inflammation Research Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, Universidad de Concepción, Concepción, Chile., Olate-Briones A; Lymphatic Vasculature and Inflammation Research Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, Universidad de Concepción, Concepción, Chile., Zagmutt S; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain., Rodríguez-Rodríguez R; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain., González DR; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile., Zúñiga-Hernandez J; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Apr 27; Vol. 17, pp. 1826739. Date of Electronic Publication: 2026 Apr 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Maresin 1 induces resolution of hepatic fibrosis through RORα-dependent reprogramming of resident macrophages.
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  Data: <searchLink fieldCode="AU" term="%22Herrera+Vielma+F%22">Herrera Vielma F</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Institute of Chemistry of Natural Resources, University of Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Quiñones+San+Martin+M%22">Quiñones San Martin M</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Institute of Chemistry of Natural Resources, University of Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Muñoz-Carrasco+N%22">Muñoz-Carrasco N</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; School of Biotechnology Engineering, Faculty of Agricultural and Forestry Sciences, Catholic University of Maule, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Berrocal-Navarrete+F%22">Berrocal-Navarrete F</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.; Faculty of Health Sciences, University of Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Herrada+AA%22">Herrada AA</searchLink>; Lymphatic Vasculature and Inflammation Research Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, Universidad de Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Olate-Briones+A%22">Olate-Briones A</searchLink>; Lymphatic Vasculature and Inflammation Research Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, Universidad de Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Zagmutt+S%22">Zagmutt S</searchLink>; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Rodríguez+R%22">Rodríguez-Rodríguez R</searchLink>; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22González+DR%22">González DR</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Zúñiga-Hernandez+J%22">Zúñiga-Hernandez J</searchLink>; Pharmacology Laboratory, Biomedical Sciences Department, Faculty of Health Sciences, University of Talca, Talca, Chile.
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