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MeCP2 Governs maternal hyperandrogenism-induced cortical defects and behavioral alterations via noncanonical AR-dependent regulation of Mef2c.

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Title: MeCP2 Governs maternal hyperandrogenism-induced cortical defects and behavioral alterations via noncanonical AR-dependent regulation of Mef2c.
Authors: Wang YM; Department of Cardiology, Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yumeng1229@126.com.; Obstetrics and Gynecology Hospital, The institute of Obstetrics and Gynecology, Shanghai key lab of reproduction and development, Shanghai key lab of female reproductive endocrine related diseases, Fudan University, Shanghai, China. yumeng1229@126.com., Jia Y; ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China., Wu Y; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China., Zhao Q; Department of Reproductive Medicine, the Second Affiliated Hospital, Medical School, Zhejiang University, Hangzhou, Zhejiang, China., Guo Y; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China., Zhang L; Department of Cardiology, Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. li.zhang@shsmu.edu.cn., Jin M; Department of Reproductive Medicine, the Second Affiliated Hospital, Medical School, Zhejiang University, Hangzhou, Zhejiang, China. min_jin@zju.edu.cn., Zheng Y; Obstetrics and Gynecology Hospital, The institute of Obstetrics and Gynecology, Shanghai key lab of reproduction and development, Shanghai key lab of female reproductive endocrine related diseases, Fudan University, Shanghai, China. zhengyf@fudan.edu.cn.
Source: Nature communications [Nat Commun] 2026 May 13; Vol. 17 (1). Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MeCP2 Governs maternal hyperandrogenism-induced cortical defects and behavioral alterations via noncanonical AR-dependent regulation of Mef2c.
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  Data: <searchLink fieldCode="AU" term="%22Wang+YM%22">Wang YM</searchLink>; Department of Cardiology, Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yumeng1229@126.com.; Obstetrics and Gynecology Hospital, The institute of Obstetrics and Gynecology, Shanghai key lab of reproduction and development, Shanghai key lab of female reproductive endocrine related diseases, Fudan University, Shanghai, China. yumeng1229@126.com.<br /><searchLink fieldCode="AU" term="%22Jia+Y%22">Jia Y</searchLink>; ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Q%22">Zhao Q</searchLink>; Department of Reproductive Medicine, the Second Affiliated Hospital, Medical School, Zhejiang University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Cardiology, Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. li.zhang@shsmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Jin+M%22">Jin M</searchLink>; Department of Reproductive Medicine, the Second Affiliated Hospital, Medical School, Zhejiang University, Hangzhou, Zhejiang, China. min_jin@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Obstetrics and Gynecology Hospital, The institute of Obstetrics and Gynecology, Shanghai key lab of reproduction and development, Shanghai key lab of female reproductive endocrine related diseases, Fudan University, Shanghai, China. zhengyf@fudan.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 13; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 13.
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        Value: 10.1038/s41467-026-72942-3
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              Text: 2026 May 13
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