Brain metabolomic profiling reveals ischemia-dominant disruption of metabolic pathways and tissue homeostasis in neonatal hypoxic-ischemic brain injury.

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Bibliographic Details
Title: Brain metabolomic profiling reveals ischemia-dominant disruption of metabolic pathways and tissue homeostasis in neonatal hypoxic-ischemic brain injury.
Authors: Wolff N; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA., Triantafyllou M; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA., Ghaemmaghami J; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA.; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Sanidas G; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA., Byrd CE; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA., Simonti G; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA., Aja S; Center for Metabolism and Obesity Research, Johns Hopkins School of Medicine, Baltimore, MD, USA., Roux A; Molecular Determinants Center and Core, Johns Hopkins All Children's Hospital, Saint Petersburg, FL, USA., Aziz K; Departments of Pediatrics, Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Goldstein E; Department of Biological Sciences, Augusta University, Augusta, GA, USA., Zhang J; Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA., Everett AD; Department of Pediatrics, Blalock-Taussig-Thomas Congenital Heart Center, Johns Hopkins University, Baltimore, MD, USA., Graham D; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kratimenos P; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA.; Department of Pediatrics, Division of Neonatology, Children's National Hospital, Washington, DC, USA.; School of Medicine and Health Sciences, George Washington University, Washington, DC, USA., Koutroulis I; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Research Institute, Washington, DC, USA. ikoutrouli@childrensnational.org.; School of Medicine and Health Sciences, George Washington University, Washington, DC, USA. ikoutrouli@childrensnational.org.; Department of Pediatrics, Division of Emergency Medicine, Children's National Hospital, Washington, DC, USA. ikoutrouli@childrensnational.org., Northington F; Departments of Pediatrics, Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. frances@jhmi.edu.
Source: Scientific reports [Sci Rep] 2026 May 14. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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