Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer.
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| Title: | Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer. |
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| Authors: | Zeng PYF; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada., Meens J; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Karimi AH; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada., Pan H; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada., Cecchini MJ; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada., Jarycki L; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada., Ryan SB; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada., Dawson AE; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada., Shaikh MH; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada., Palma DA; Department of Oncology, Western University, London, ON, Canada., Winquist E; Department of Oncology, Western University, London, ON, Canada., Gunaratnam L; Department of Microbiology & Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre Research Institute, London Health Sciences Centre, London, ON, Canada., Mymryk JS; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada; Department of Microbiology & Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Barrett JW; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada., Boutros PC; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, USA., Ailles L; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address: laurie.ailles@uhn.ca., Nichols AC; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada. Electronic address: anthony.nichols@lhsc.on.ca. |
| Source: | Cell reports. Medicine [Cell Rep Med] 2026 Jun 16; Vol. 7 (6), pp. 102820. Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42143022 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zeng+PYF%22">Zeng PYF</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Meens+J%22">Meens J</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Karimi+AH%22">Karimi AH</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pan+H%22">Pan H</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Cecchini+MJ%22">Cecchini MJ</searchLink>; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Jarycki+L%22">Jarycki L</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ryan+SB%22">Ryan SB</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Dawson+AE%22">Dawson AE</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Shaikh+MH%22">Shaikh MH</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Palma+DA%22">Palma DA</searchLink>; Department of Oncology, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Winquist+E%22">Winquist E</searchLink>; Department of Oncology, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gunaratnam+L%22">Gunaratnam L</searchLink>; Department of Microbiology & Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre Research Institute, London Health Sciences Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mymryk+JS%22">Mymryk JS</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada; Department of Microbiology & Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Barrett+JW%22">Barrett JW</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Boutros+PC%22">Boutros PC</searchLink>; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ailles+L%22">Ailles L</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address: laurie.ailles@uhn.ca.<br /><searchLink fieldCode="AU" term="%22Nichols+AC%22">Nichols AC</searchLink>; Department of Otolaryngology - Head & Neck Surgery, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada. Electronic address: anthony.nichols@lhsc.on.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2026 Jun 16; Vol. 7 (6), pp. 102820. <i>Date of Electronic Publication: </i>2026 May 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101766894 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-3791 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226663791%22">26663791 </searchLink><i>NLM ISO Abbreviation: </i>Cell Rep Med <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.xcrm.2026.102820 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 102820 Titles: – TitleFull: Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zeng PYF – PersonEntity: Name: NameFull: Meens J – PersonEntity: Name: NameFull: Karimi AH – PersonEntity: Name: NameFull: Pan H – PersonEntity: Name: NameFull: Cecchini MJ – PersonEntity: Name: NameFull: Jarycki L – PersonEntity: Name: NameFull: Ryan SB – PersonEntity: Name: NameFull: Dawson AE – PersonEntity: Name: NameFull: Shaikh MH – PersonEntity: Name: NameFull: Palma DA – PersonEntity: Name: NameFull: Winquist E – PersonEntity: Name: NameFull: Gunaratnam L – PersonEntity: Name: NameFull: Mymryk JS – PersonEntity: Name: NameFull: Barrett JW – PersonEntity: Name: NameFull: Boutros PC – PersonEntity: Name: NameFull: Ailles L – PersonEntity: Name: NameFull: Nichols AC IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 06 Text: 2026 Jun 16 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2666-3791 Numbering: – Type: volume Value: 7 – Type: issue Value: 6 Titles: – TitleFull: Cell reports. Medicine Type: main |
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