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Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption.

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Title: Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption.
Authors: de Lucena FS; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Logan MG; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Lewis SH; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Zhang H; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Barbisan M; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Icimoto MY; Department of Biophysics, Federal University of Sao Paulo,UNIFESP-EPM, Sao Paulo, Brazil., Wu H; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Higashi D; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Merritt JL; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Baker JL; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA., Pfeifer CS; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA. pfeiferc@ohsu.edu.
Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2026 May 16. Date of Electronic Publication: 2026 May 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption.
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  Data: <searchLink fieldCode="AU" term="%22de+Lucena+FS%22">de Lucena FS</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Logan+MG%22">Logan MG</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+SH%22">Lewis SH</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Barbisan+M%22">Barbisan M</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Icimoto+MY%22">Icimoto MY</searchLink>; Department of Biophysics, Federal University of Sao Paulo,UNIFESP-EPM, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Higashi+D%22">Higashi D</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Merritt+JL%22">Merritt JL</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Baker+JL%22">Baker JL</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Pfeifer+CS%22">Pfeifer CS</searchLink>; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health & Science University, OHSU, Portland, OR, USA. pfeiferc@ohsu.edu.
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  Data: <searchLink fieldCode="JN" term="%22101666944%22">NPJ biofilms and microbiomes</searchLink> [NPJ Biofilms Microbiomes] 2026 May 16. <i>Date of Electronic Publication: </i>2026 May 16.
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        Value: 10.1038/s41522-026-01006-7
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              Text: 2026 May 16
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