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Complete response in metastatic clear cell renal cell carcinoma following pembrolizumab-axitinib and subsequent nephrectomy: a Case Report.

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Title: Complete response in metastatic clear cell renal cell carcinoma following pembrolizumab-axitinib and subsequent nephrectomy: a Case Report.
Authors: Polito MG; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy., Caruso D; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy., Cosimati A; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy., Ramirez Reinaga CA; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy., Leka E; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy., Fuschi A; Department of Urology Università 'La Sapienza', ICOT Polo Pontino, Latina, Italy., Pastore AL; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy., Carbone A; Department of Urology Università 'La Sapienza', ICOT Polo Pontino, Latina, Italy., Lako K; Department of Medico-Surgical Sciences and Biotechnologies Histopathology, Sapienza University of Rome Faculty of Pharmacy and Medicine, Latina, Italy., Di Cristofano C; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy., Petrozza V; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy., Santini D; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy., Spinelli GP; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.
Source: Frontiers in immunology [Front Immunol] 2026 May 01; Vol. 17, pp. 1811163. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Polito+MG%22">Polito MG</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Caruso+D%22">Caruso D</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Cosimati+A%22">Cosimati A</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Ramirez+Reinaga+CA%22">Ramirez Reinaga CA</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Leka+E%22">Leka E</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Fuschi+A%22">Fuschi A</searchLink>; Department of Urology Università 'La Sapienza', ICOT Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Pastore+AL%22">Pastore AL</searchLink>; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Carbone+A%22">Carbone A</searchLink>; Department of Urology Università 'La Sapienza', ICOT Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Lako+K%22">Lako K</searchLink>; Department of Medico-Surgical Sciences and Biotechnologies Histopathology, Sapienza University of Rome Faculty of Pharmacy and Medicine, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Cristofano+C%22">Di Cristofano C</searchLink>; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Petrozza+V%22">Petrozza V</searchLink>; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Santini+D%22">Santini D</searchLink>; Department of Medical and Surgical Science and Biotechnology, Università 'La Sapienza', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Spinelli+GP%22">Spinelli GP</searchLink>; UOC Oncologia Territoriale - ASL Latina - CDS Aprilia, La Sapienza Università Di Roma Polo Pontino, Latina, Italy.
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