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De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer.

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Title: De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer.
Authors: Hidalgo CM; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Bogan AW; Department of Quantitative Health Sciences, Division of Biostatistics, Mayo Clinic, Scottsdale, Arizona., Rourk KS; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Baratz HQ; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Eyassu DG; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Price KA; Division of Oncology, Mayo Clinic, Rochester, Minnesota., Moore EJ; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Patel SH; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona., Hinni ML; Department of Otolaryngology, Mayo Clinic, Phoenix, Arizona., Neben-Wittich MA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Garces YI; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., McGee LA; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona., Lester SC; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Wilson J; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Rwigema JM; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona., Chintakuntlawar AV; Division of Medical Oncology, Mayo Clinic, Phoenix, Arizona., Mohammadi H; Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida., Holtzman AL; Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida., Price DL; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Janus JR; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Jacksonville, Florida., Garcia JJ; Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota., Foote RL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Tasche KK; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Ma DJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Van Abel KM; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Yin LX; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota., Routman DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
Source: JAMA network open [JAMA Netw Open] 2026 May 01; Vol. 9 (5), pp. e2612837. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE; In Process
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  Data: De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Hidalgo+CM%22">Hidalgo CM</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Bogan+AW%22">Bogan AW</searchLink>; Department of Quantitative Health Sciences, Division of Biostatistics, Mayo Clinic, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Rourk+KS%22">Rourk KS</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Baratz+HQ%22">Baratz HQ</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Eyassu+DG%22">Eyassu DG</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Price+KA%22">Price KA</searchLink>; Division of Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Moore+EJ%22">Moore EJ</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Patel+SH%22">Patel SH</searchLink>; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Hinni+ML%22">Hinni ML</searchLink>; Department of Otolaryngology, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Neben-Wittich+MA%22">Neben-Wittich MA</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Garces+YI%22">Garces YI</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22McGee+LA%22">McGee LA</searchLink>; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Lester+SC%22">Lester SC</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Wilson+J%22">Wilson J</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Rwigema+JM%22">Rwigema JM</searchLink>; Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Chintakuntlawar+AV%22">Chintakuntlawar AV</searchLink>; Division of Medical Oncology, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Mohammadi+H%22">Mohammadi H</searchLink>; Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Holtzman+AL%22">Holtzman AL</searchLink>; Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Price+DL%22">Price DL</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Janus+JR%22">Janus JR</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Garcia+JJ%22">Garcia JJ</searchLink>; Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Foote+RL%22">Foote RL</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Tasche+KK%22">Tasche KK</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Ma+DJ%22">Ma DJ</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Van+Abel+KM%22">Van Abel KM</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Yin+LX%22">Yin LX</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Routman+DM%22">Routman DM</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
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