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Targeting fusion proteins in solid tumors: from oncogenic mechanisms to clinical interventions.

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Title: Targeting fusion proteins in solid tumors: from oncogenic mechanisms to clinical interventions.
Authors: Yang YN; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Chen YF; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Yang DL; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Ying WW; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., He QJ; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China.; Cancer Center, Zhejiang University, Hangzhou, 310058, China., Ying MD; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. mying@zju.edu.cn.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China. mying@zju.edu.cn.; Cancer Center, Zhejiang University, Hangzhou, 310058, China. mying@zju.edu.cn., Yang B; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yang924@zju.edu.cn.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China. yang924@zju.edu.cn.; Cancer Center, Zhejiang University, Hangzhou, 310058, China. yang924@zju.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 May 18. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting fusion proteins in solid tumors: from oncogenic mechanisms to clinical interventions.
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  Data: <searchLink fieldCode="AU" term="%22Yang+YN%22">Yang YN</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Chen+YF%22">Chen YF</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Yang+DL%22">Yang DL</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Ying+WW%22">Ying WW</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22He+QJ%22">He QJ</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China.; Cancer Center, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Ying+MD%22">Ying MD</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. mying@zju.edu.cn.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China. mying@zju.edu.cn.; Cancer Center, Zhejiang University, Hangzhou, 310058, China. mying@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+B%22">Yang B</searchLink>; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yang924@zju.edu.cn.; Engineering Research Center of Innovative Anticancer Drugs, Ministry of Education, Hangzhou, 310058, China. yang924@zju.edu.cn.; Cancer Center, Zhejiang University, Hangzhou, 310058, China. yang924@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2026 May 18. <i>Date of Electronic Publication: </i>2026 May 18.
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        Value: 10.1038/s41401-026-01817-6
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              Text: 2026 May 18
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