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Identification of gene conversion events in horse IGHV suggests preferential hotspots for diversification.

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Title: Identification of gene conversion events in horse IGHV suggests preferential hotspots for diversification.
Authors: Pinto JEL; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Gervásio JHB; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.; Model-Based Evolutionary Genomic Unit, Okinawa Institute of Science and Technology (OIST), Tancha, 904-0412, Okinawa, Japan., Ng JC; Research Department of Structural and Molecular Biology, University College London, London, WC1E 6BT, UK., Gomes-Silva A; Interdisciplinary Laboratory of Medical Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; Mycobacteriosis Clinical Research Laboratory, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil., de Matos Guedes HL; Laboratory of Immunobiotechnology, Department of Immunology, Paulo de Góes Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Laboratory of Clinical Immunology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil., Cunha L; Vital Brazil Institute, Niterói, RJ, Brazil., Castilho LR; Cell Culture Engineering Laboratory, COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., da Silva JL; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Franco GR; Laboratory of Biochemical Genetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, 30161-970, Brazil., Navas C; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Felicori LF; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. lizaffelicori@gmail.com.
Source: Immunogenetics [Immunogenetics] 2026 May 19; Vol. 78 (1). Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 0420404 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1211 (Electronic) Linking ISSN: 00937711 NLM ISO Abbreviation: Immunogenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of gene conversion events in horse IGHV suggests preferential hotspots for diversification.
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  Data: <searchLink fieldCode="AU" term="%22Pinto+JEL%22">Pinto JEL</searchLink>; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Gervásio+JHB%22">Gervásio JHB</searchLink>; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.; Model-Based Evolutionary Genomic Unit, Okinawa Institute of Science and Technology (OIST), Tancha, 904-0412, Okinawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ng+JC%22">Ng JC</searchLink>; Research Department of Structural and Molecular Biology, University College London, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Gomes-Silva+A%22">Gomes-Silva A</searchLink>; Interdisciplinary Laboratory of Medical Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; Mycobacteriosis Clinical Research Laboratory, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Matos+Guedes+HL%22">de Matos Guedes HL</searchLink>; Laboratory of Immunobiotechnology, Department of Immunology, Paulo de Góes Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Laboratory of Clinical Immunology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Cunha+L%22">Cunha L</searchLink>; Vital Brazil Institute, Niterói, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Castilho+LR%22">Castilho LR</searchLink>; Cell Culture Engineering Laboratory, COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+JL%22">da Silva JL</searchLink>; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Franco+GR%22">Franco GR</searchLink>; Laboratory of Biochemical Genetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, 30161-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Navas+C%22">Navas C</searchLink>; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Felicori+LF%22">Felicori LF</searchLink>; Laboratory of Synthetic Biology and Biomimetics, Department of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. lizaffelicori@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%220420404%22">Immunogenetics</searchLink> [Immunogenetics] 2026 May 19; Vol. 78 (1). <i>Date of Electronic Publication: </i>2026 May 19.
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              Text: 2026 May 19
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