Effects of inflammatory phenotypes in acute respiratory distress syndrome on mortality and partitioning of lung and chest wall mechanics in patients in the USA and Canada: a retrospective cohort study.

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Title: Effects of inflammatory phenotypes in acute respiratory distress syndrome on mortality and partitioning of lung and chest wall mechanics in patients in the USA and Canada: a retrospective cohort study.
Authors: Pensier J; Anesthesiology and Intensive Care, Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, Montpellier, France; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Fosset M; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Medical Intensive Care Unit, Premedical Inria-Inserm Team Idesp, Montpellier University and Montpellier University Health Care Center, Montpellier, France., Paschold BS; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, University of Ulm, Ulm, Germany., von Wedel D; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Institute of Medical Informatics, Charité-Universitätsmedizin Berlin, Berlin, Germany., Sharif M; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Braeuer BLP; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Sahli SD; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland., Novack V; Clinical Research Center, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Goodspeed V; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Sarge T; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Jung B; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Medical Intensive Care Unit, Premedical Inria-Inserm Team Idesp, Montpellier University and Montpellier University Health Care Center, Montpellier, France; Department of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Amato MBP; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Laboratório de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute [Incor], São Paulo, Brazil., Sinha P; Department of Anesthesia, Division of Clinical and Translational Research, Washington University School of Medicine, St Louis, MO, USA., Talmor D; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Schaefer MS; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Anesthesiology, Duesseldorf University Hospital, Duesseldorf, Germany. Electronic address: msschaef@bidmc.harvard.edu., Baedorf-Kassis E; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2026 May 19. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE
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  Data: Effects of inflammatory phenotypes in acute respiratory distress syndrome on mortality and partitioning of lung and chest wall mechanics in patients in the USA and Canada: a retrospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Pensier+J%22">Pensier J</searchLink>; Anesthesiology and Intensive Care, Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, Montpellier, France; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fosset+M%22">Fosset M</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Medical Intensive Care Unit, Premedical Inria-Inserm Team Idesp, Montpellier University and Montpellier University Health Care Center, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Paschold+BS%22">Paschold BS</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22von+Wedel+D%22">von Wedel D</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Institute of Medical Informatics, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sharif+M%22">Sharif M</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Braeuer+BLP%22">Braeuer BLP</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sahli+SD%22">Sahli SD</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland.<br /><searchLink fieldCode="AU" term="%22Novack+V%22">Novack V</searchLink>; Clinical Research Center, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Goodspeed+V%22">Goodspeed V</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sarge+T%22">Sarge T</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jung+B%22">Jung B</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Medical Intensive Care Unit, Premedical Inria-Inserm Team Idesp, Montpellier University and Montpellier University Health Care Center, Montpellier, France; Department of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amato+MBP%22">Amato MBP</searchLink>; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Laboratório de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute [Incor], São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Sinha+P%22">Sinha P</searchLink>; Department of Anesthesia, Division of Clinical and Translational Research, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Talmor+D%22">Talmor D</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schaefer+MS%22">Schaefer MS</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Anesthesiology, Duesseldorf University Hospital, Duesseldorf, Germany. Electronic address: msschaef@bidmc.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Baedorf-Kassis+E%22">Baedorf-Kassis E</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Department of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
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