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Diphenyl Disulfide Induces Nonapoptotic Paraptosis in Breast Cancer Cells via ROS-Mediated ER Stress.

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Title: Diphenyl Disulfide Induces Nonapoptotic Paraptosis in Breast Cancer Cells via ROS-Mediated ER Stress.
Authors: Chen SY; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Zuoying Armed Forces General Hospital, Kaohsiung 813, Taiwan., Wu CY; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan.; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Pan WH; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan., Hsu SK; PhD Program in Life Sciences, College of Life Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Chang WT; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Chen YC; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan., He CX; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Shu ED; PhD Program in Life Sciences, College of Life Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Wen ZH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; National Museum of Marine Biology & Aquarium, Pingtung, 944, Taiwan., Chiu CC; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan.; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Source: International journal of medical sciences [Int J Med Sci] 2026 May 01; Vol. 23 (6), pp. 2096-2107. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE
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  Data: Diphenyl Disulfide Induces Nonapoptotic Paraptosis in Breast Cancer Cells via ROS-Mediated ER Stress.
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  Data: <searchLink fieldCode="AU" term="%22Chen+SY%22">Chen SY</searchLink>; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Zuoying Armed Forces General Hospital, Kaohsiung 813, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CY%22">Wu CY</searchLink>; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan.; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pan+WH%22">Pan WH</searchLink>; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+SK%22">Hsu SK</searchLink>; PhD Program in Life Sciences, College of Life Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+WT%22">Chang WT</searchLink>; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22He+CX%22">He CX</searchLink>; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shu+ED%22">Shu ED</searchLink>; PhD Program in Life Sciences, College of Life Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wen+ZH%22">Wen ZH</searchLink>; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; National Museum of Marine Biology & Aquarium, Pingtung, 944, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+CC%22">Chiu CC</searchLink>; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, 804, Taiwan.; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101213954%22">International journal of medical sciences</searchLink> [Int J Med Sci] 2026 May 01; Vol. 23 (6), pp. 2096-2107. <i>Date of Electronic Publication: </i>2026 May 01 (<i>Print Publication: </i>2026).
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              Text: 2026 May 01
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