Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation.
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| Title: | Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation. |
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| Authors: | Lee H; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA., Dunn A; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA., Taylor SE; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chauhan A; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Ivy SP; Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA., Gobburu J; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA., Beumer JH; Cancer Therapeutics Program, UPMC Hillman Cancer Centre, Pittsburgh, PA, USA. jan.beumer@jhu.edu.; Department of Oncology, Johns Hopkins University School of Medicine and Johns Hopkins Sidney Kimmel Cancer Center, 1650 Orleans St, Room 1M52, Baltimore, MD, 21287, USA. jan.beumer@jhu.edu. |
| Source: | Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2026 May 20; Vol. 96 (1). Date of Electronic Publication: 2026 May 20. |
| Publication Type: | Journal Article; Clinical Trial, Phase I |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42159774 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA.<br /><searchLink fieldCode="AU" term="%22Dunn+A%22">Dunn A</searchLink>; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+SE%22">Taylor SE</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chauhan+A%22">Chauhan A</searchLink>; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ivy+SP%22">Ivy SP</searchLink>; Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gobburu+J%22">Gobburu J</searchLink>; Center for Translational Medicine, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD, 21201, USA.<br /><searchLink fieldCode="AU" term="%22Beumer+JH%22">Beumer JH</searchLink>; Cancer Therapeutics Program, UPMC Hillman Cancer Centre, Pittsburgh, PA, USA. jan.beumer@jhu.edu.; Department of Oncology, Johns Hopkins University School of Medicine and Johns Hopkins Sidney Kimmel Cancer Center, 1650 Orleans St, Room 1M52, Baltimore, MD, 21287, USA. jan.beumer@jhu.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227806519%22">Cancer chemotherapy and pharmacology</searchLink> [Cancer Chemother Pharmacol] 2026 May 20; Vol. 96 (1). <i>Date of Electronic Publication: </i>2026 May 20. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7806519 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0843 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203445704%22">03445704 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Chemother Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42159774 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00280-026-04898-6 Languages: – Code: eng Text: English Titles: – TitleFull: Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lee H – PersonEntity: Name: NameFull: Dunn A – PersonEntity: Name: NameFull: Taylor SE – PersonEntity: Name: NameFull: Chauhan A – PersonEntity: Name: NameFull: Ivy SP – PersonEntity: Name: NameFull: Gobburu J – PersonEntity: Name: NameFull: Beumer JH IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 05 Text: 2026 May 20 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1432-0843 Numbering: – Type: volume Value: 96 – Type: issue Value: 1 Titles: – TitleFull: Cancer chemotherapy and pharmacology Type: main |
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