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TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15.

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Title: TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15.
Authors: Shyer JA; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Wehbe F; Roche Informatics, F. Hoffmann-La Roche Ltd., Mississauga, ON L5N 5M8, Canada., Davidson CD; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Bender HS; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Thai M; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Cox C; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Missarova A; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Arlantico A; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Hall B; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Zhang R; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Kim D; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Altieri A; Department of Immunology, University of Toronto, Toronto, ON M5S 3G9, Canada., Hasan S; Department of Immunology, University of Toronto, Toronto, ON M5S 3G9, Canada., Namdar A; Department of Immunology, University of Toronto, Toronto, ON M5S 3G9, Canada., Chen T; Hospital for Sick Children Research Institute, Toronto, ON M5G 1E8, Canada., Hakim SW; St. Joseph's Health Centre, Unity Health Toronto, Toronto, ON M6R 1B5, Canada., Guidos C; Hospital for Sick Children Research Institute, Toronto, ON M5G 1E8, Canada., Brightbill HD; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Kuo T; Roche Informatics, F. Hoffmann-La Roche Ltd., Mississauga, ON L5N 5M8, Canada., Heimberg G; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Corrada Bravo H; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Ratsimandresy RA; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Uttarwar S; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Teng G; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Salem O; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Arjomandi M; Department of Medicine, University of California San Francisco, San Francisco, CA 94143., Wilson MS; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Darmanis S; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Ziai J; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Scherl A; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Modrusan Z; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Wolters PJ; Department of Medicine, University of California San Francisco, San Francisco, CA 94143., Buechler MB; Department of Immunology, University of Toronto, Toronto, ON M5S 3G9, Canada.; Schroeder Arthritis Institute, University Health Network, Toronto, ON M5G 2C4, Canada., Vander Heiden JA; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080., Turley SJ; Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA 94080.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 26; Vol. 123 (21), pp. e2536550123. Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 May 26; Vol. 123 (21), pp. e2536550123. <i>Date of Electronic Publication: </i>2026 May 20.
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