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2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease.

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Title: 2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease.
Authors: Saeed A; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Mckennan C; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Clougherty JE; Drexel University, Philadelphia, Pennsylvania, USA., Zhou P; University of Texas Health Sciences, Houston, Texas, USA., Tripathy S; Drexel University, Philadelphia, Pennsylvania, USA., Kinnee EJ; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Duan J; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kip K; UPMC Analytics, UPMC, Pittsburgh, Pennsylvania, USA., Zeng X; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, UPMC, Pittsburgh, Pennsylvania, USA., Villemagne V; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Pascoal T; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Mapstone M; University of California Irvine, Irvine, California, USA., Whitsel EA; University of North Carolina, Chapel Hill, North Carolina, USA., Lopez OI; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ballantyne C; Baylor College of Medicine, Houston, Texas, USA., Karikari TK; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, UPMC, Pittsburgh, Pennsylvania, USA., Yu B; University of Texas Health Sciences, Houston, Texas, USA., Reis S; University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Cohen A; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 May; Vol. 22 (5), pp. e71388.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Saeed+A%22">Saeed A</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Mckennan+C%22">Mckennan C</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Clougherty+JE%22">Clougherty JE</searchLink>; Drexel University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+P%22">Zhou P</searchLink>; University of Texas Health Sciences, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Tripathy+S%22">Tripathy S</searchLink>; Drexel University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kinnee+EJ%22">Kinnee EJ</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Duan+J%22">Duan J</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kip+K%22">Kip K</searchLink>; UPMC Analytics, UPMC, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, UPMC, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Villemagne+V%22">Villemagne V</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Pascoal+T%22">Pascoal T</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Mapstone+M%22">Mapstone M</searchLink>; University of California Irvine, Irvine, California, USA.<br /><searchLink fieldCode="AU" term="%22Whitsel+EA%22">Whitsel EA</searchLink>; University of North Carolina, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Lopez+OI%22">Lopez OI</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ballantyne+C%22">Ballantyne C</searchLink>; Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Karikari+TK%22">Karikari TK</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, UPMC, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; University of Texas Health Sciences, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Reis+S%22">Reis S</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+A%22">Cohen A</searchLink>; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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              Text: 2026 May
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