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Spheroids reveal hypoxia‑driven spatial restriction of adenoviral infection.

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Title: Spheroids reveal hypoxia‑driven spatial restriction of adenoviral infection.
Authors: Büttner T; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Wang X; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Krishnacoumar B; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Papadamakis A; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Cicek S; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Schild Y; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Winning S; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Littwitz-Salomon E; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.; Institute for the Research on HIV and AIDS-associated Diseases, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Ehrhardt A; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Faculty of Health, Witten/Herdecke University, Witten, Germany., Dittmer U; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Bayer W; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Fandrey J; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany., Malyshkina A; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. anna.malyshkina@uk-essen.de.
Source: Scientific reports [Sci Rep] 2026 May 21; Vol. 16 (1). Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Büttner+T%22">Büttner T</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Krishnacoumar+B%22">Krishnacoumar B</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Papadamakis+A%22">Papadamakis A</searchLink>; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Cicek+S%22">Cicek S</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Schild+Y%22">Schild Y</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Winning+S%22">Winning S</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Littwitz-Salomon+E%22">Littwitz-Salomon E</searchLink>; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.; Institute for the Research on HIV and AIDS-associated Diseases, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Ehrhardt+A%22">Ehrhardt A</searchLink>; Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Faculty of Health, Witten/Herdecke University, Witten, Germany.<br /><searchLink fieldCode="AU" term="%22Dittmer+U%22">Dittmer U</searchLink>; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Bayer+W%22">Bayer W</searchLink>; Institute for Virology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Fandrey+J%22">Fandrey J</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Malyshkina+A%22">Malyshkina A</searchLink>; Institute of Physiology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. anna.malyshkina@uk-essen.de.
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