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Trifluridine/tipiracil enhances radiation-induced abscopal effects and augments PD-1 blockade in gastric cancer.

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Title: Trifluridine/tipiracil enhances radiation-induced abscopal effects and augments PD-1 blockade in gastric cancer.
Authors: Asakawa T; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Kinoshita J; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan. junkino0416@gmail.com., Doden K; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Hayashi K; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Hayashi S; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Saito H; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Tsuji T; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Yamamoto D; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Moriyama H; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan., Nomura S; Clinical Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, 142-8501, Japan.; Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.; Department of Gastrointestinal Surgery, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, 113-8655, Japan., Yamamoto Y; Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, 920-8640, Ishikawa, Japan., Inaki N; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.
Source: Scientific reports [Sci Rep] 2026 May 21. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Trifluridine/tipiracil enhances radiation-induced abscopal effects and augments PD-1 blockade in gastric cancer.
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  Data: <searchLink fieldCode="AU" term="%22Asakawa+T%22">Asakawa T</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kinoshita+J%22">Kinoshita J</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan. junkino0416@gmail.com.<br /><searchLink fieldCode="AU" term="%22Doden+K%22">Doden K</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+K%22">Hayashi K</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+S%22">Hayashi S</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+H%22">Saito H</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuji+T%22">Tsuji T</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+D%22">Yamamoto D</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Moriyama+H%22">Moriyama H</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Nomura+S%22">Nomura S</searchLink>; Clinical Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, 142-8501, Japan.; Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.; Department of Gastrointestinal Surgery, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, 113-8655, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+Y%22">Yamamoto Y</searchLink>; Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, 920-8640, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Inaki+N%22">Inaki N</searchLink>; Department of Gastrointestinal Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Ishikawa, Japan.
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              Text: 2026 May 21
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