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Shorter to be effective: subanesthetic-dose ketamine infusion reduces the global and regional path length of brain functional connectivity in patients with treatment-resistant depression and suicidal ideation.

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Title: Shorter to be effective: subanesthetic-dose ketamine infusion reduces the global and regional path length of brain functional connectivity in patients with treatment-resistant depression and suicidal ideation.
Authors: Lin WC; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Cheng LK; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Su TP; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Psychiatry, General Cheng Hsin Hospital, Taipei, Taiwan.; Brain Research Centre, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen LF; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Brain Research Centre, National Yang Ming Chiao Tung University, Taipei, Taiwan., Tu PC; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Philosophy of Mind and Cognition, National Yang Ming Chiao Tung University, Taipei, Taiwan., Li CT; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Bai YM; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Tsai SJ; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen MH; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan. kremer7119@gmail.com.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. kremer7119@gmail.com.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan. kremer7119@gmail.com.
Source: Psychopharmacology [Psychopharmacology (Berl)] 2026 May 22. Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lin+WC%22">Lin WC</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+LK%22">Cheng LK</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+TP%22">Su TP</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Psychiatry, General Cheng Hsin Hospital, Taipei, Taiwan.; Brain Research Centre, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+LF%22">Chen LF</searchLink>; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Brain Research Centre, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tu+PC%22">Tu PC</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Philosophy of Mind and Cognition, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+CT%22">Li CT</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Bai+YM%22">Bai YM</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+SJ%22">Tsai SJ</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+MH%22">Chen MH</searchLink>; Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, 112, Taiwan. kremer7119@gmail.com.; Division of Psychiatry, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. kremer7119@gmail.com.; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan. kremer7119@gmail.com.
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        Value: 10.1007/s00213-026-07089-6
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        Text: English
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            – D: 22
              M: 05
              Text: 2026 May 22
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              Y: 2026
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