Genetic ablation of neuronal mitochondrial calcium uptake impedes Alzheimer's disease progression.

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Title: Genetic ablation of neuronal mitochondrial calcium uptake impedes Alzheimer's disease progression.
Authors: Jadiya P; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Berezhnaya E; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Kolmetzky DW; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Tomar D; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Cohen HM; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Shukla S; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Thomas M; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Khaledi S; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Garbincius JF; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Kennedy L; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Salik O; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Raghav D; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Hildebrand AN; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA., Elrod JW; Aging + Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. elrod@temple.edu.
Source: The EMBO journal [EMBO J] 2026 May 22. Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
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  Data: Genetic ablation of neuronal mitochondrial calcium uptake impedes Alzheimer's disease progression.
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