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Real-world uptake of gBRCA testing as a companion diagnostic for olaparib in patients with high-risk HER2-negative early breast cancer in Japan: a cross-sectional multicenter study (BRCAwareness).

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Title: Real-world uptake of gBRCA testing as a companion diagnostic for olaparib in patients with high-risk HER2-negative early breast cancer in Japan: a cross-sectional multicenter study (BRCAwareness).
Authors: Taji T; Department of Breast Surgery, Kansai Medical University, 3-1 Shinmachi 2 Chome, Hirakata, Osaka, 573-1191, Japan. taji.tom@kmu.ac.jp., Uemura Y; Laboratory of Biostatistics, Department of Data Science, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan., Kimura Y; Department of Breast Surgical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan., Maeda N; Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1, Minami Kogushi, , Ube, Yamaguchi, 755-8505, Japan., Ito A; Department of Breast Surgery, Akita Red Cross Hospital, 222-1 Kamikitatesarutanawashirosawa, Akita, Akita, 010-1495, Japan., Seki H; Department of Breast Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka Meguro-ku, Tokyo, 152-8902, Japan., Takabatake D; Department of Breast Surgery, National Hospital Organization Shikoku Cancer Center, 160 Minamiumemotomachi, Matsuyama, Ehime, 791- 0245, Japan., Harao M; Department of Breast Oncology, Jichi Medical University, 3311-1 Yakushiji, , Shimotsuke, Tochigi, 329-0498, Japan., Nakamoto S; Department of Breast and Endocrine Surgery, Okayama University Hospital, 2-5-1 Shikata-cho, Kitaku, Okayama, 700-8558, Japan., Matsunuma R; Department of Breast Surgery, Shizuoka General Hospital, 4-27-1 Kita-ando, Aoi-ku, Shizuoka, 420-8527, Japan., Koganezawa C; Department of Breast Oncology, Hokkaido Cancer Center, 2-3-54 Kikusui 4-jo, Shiroishi-ku, Sapporo, Hokkaido, 003-0804, Japan., Iwamoto T; Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan., Mukai H; Department of Medical Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Kikawa Y; Department of Breast Surgery, Kansai Medical University, 3-1 Shinmachi 2 Chome, Hirakata, Osaka, 573-1191, Japan.
Source: Breast cancer (Tokyo, Japan) [Breast Cancer] 2026 Jul; Vol. 33 (4), pp. 919-927. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Maruzen Co Country of Publication: Japan NLM ID: 100888201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-4233 (Electronic) Linking ISSN: 13406868 NLM ISO Abbreviation: Breast Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world uptake of gBRCA testing as a companion diagnostic for olaparib in patients with high-risk HER2-negative early breast cancer in Japan: a cross-sectional multicenter study (BRCAwareness).
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  Data: <searchLink fieldCode="AU" term="%22Taji+T%22">Taji T</searchLink>; Department of Breast Surgery, Kansai Medical University, 3-1 Shinmachi 2 Chome, Hirakata, Osaka, 573-1191, Japan. taji.tom@kmu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Uemura+Y%22">Uemura Y</searchLink>; Laboratory of Biostatistics, Department of Data Science, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+Y%22">Kimura Y</searchLink>; Department of Breast Surgical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Maeda+N%22">Maeda N</searchLink>; Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1, Minami Kogushi, , Ube, Yamaguchi, 755-8505, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+A%22">Ito A</searchLink>; Department of Breast Surgery, Akita Red Cross Hospital, 222-1 Kamikitatesarutanawashirosawa, Akita, Akita, 010-1495, Japan.<br /><searchLink fieldCode="AU" term="%22Seki+H%22">Seki H</searchLink>; Department of Breast Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka Meguro-ku, Tokyo, 152-8902, Japan.<br /><searchLink fieldCode="AU" term="%22Takabatake+D%22">Takabatake D</searchLink>; Department of Breast Surgery, National Hospital Organization Shikoku Cancer Center, 160 Minamiumemotomachi, Matsuyama, Ehime, 791- 0245, Japan.<br /><searchLink fieldCode="AU" term="%22Harao+M%22">Harao M</searchLink>; Department of Breast Oncology, Jichi Medical University, 3311-1 Yakushiji, , Shimotsuke, Tochigi, 329-0498, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamoto+S%22">Nakamoto S</searchLink>; Department of Breast and Endocrine Surgery, Okayama University Hospital, 2-5-1 Shikata-cho, Kitaku, Okayama, 700-8558, Japan.<br /><searchLink fieldCode="AU" term="%22Matsunuma+R%22">Matsunuma R</searchLink>; Department of Breast Surgery, Shizuoka General Hospital, 4-27-1 Kita-ando, Aoi-ku, Shizuoka, 420-8527, Japan.<br /><searchLink fieldCode="AU" term="%22Koganezawa+C%22">Koganezawa C</searchLink>; Department of Breast Oncology, Hokkaido Cancer Center, 2-3-54 Kikusui 4-jo, Shiroishi-ku, Sapporo, Hokkaido, 003-0804, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+T%22">Iwamoto T</searchLink>; Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Mukai+H%22">Mukai H</searchLink>; Department of Medical Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Kikawa+Y%22">Kikawa Y</searchLink>; Department of Breast Surgery, Kansai Medical University, 3-1 Shinmachi 2 Chome, Hirakata, Osaka, 573-1191, Japan.
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  Data: <searchLink fieldCode="JN" term="%22100888201%22">Breast cancer (Tokyo, Japan)</searchLink> [Breast Cancer] 2026 Jul; Vol. 33 (4), pp. 919-927. <i>Date of Electronic Publication: </i>2026 May 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Maruzen+Co%22">Maruzen Co </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>100888201 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-4233 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213406868%22">13406868 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s12282-026-01867-y
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        Text: English
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        StartPage: 919
    Titles:
      – TitleFull: Real-world uptake of gBRCA testing as a companion diagnostic for olaparib in patients with high-risk HER2-negative early breast cancer in Japan: a cross-sectional multicenter study (BRCAwareness).
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              Text: 2026 Jul
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