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S3I-201, a STAT3 Inhibitor, Inhibits Proinflammatory Mediator Signalling in CD19 and CD45R/B220 Cells in a Mouse Model of Multiple Sclerosis.

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Title: S3I-201, a STAT3 Inhibitor, Inhibits Proinflammatory Mediator Signalling in CD19 and CD45R/B220 Cells in a Mouse Model of Multiple Sclerosis.
Authors: Alsaad AMS; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Nadeem A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Attia SM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Ansari MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Bakheet SA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Algonaiah MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Al-Mazroua HA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Alomar HA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Sarawi WS; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Almutairi MM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Aldossari AA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Saquib Q; Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia., Algarzae NK; Department of Physiology, College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia., Mahmoud MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Hussein MH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Ahmad SF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia. fashaikh@ksu.edu.sa.
Source: Cellular and molecular neurobiology [Cell Mol Neurobiol] 2026 May 24. Date of Electronic Publication: 2026 May 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8200709 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6830 (Electronic) Linking ISSN: 02724340 NLM ISO Abbreviation: Cell Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: S3I-201, a STAT3 Inhibitor, Inhibits Proinflammatory Mediator Signalling in CD19 and CD45R/B220 Cells in a Mouse Model of Multiple Sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Alsaad+AMS%22">Alsaad AMS</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nadeem+A%22">Nadeem A</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Attia+SM%22">Attia SM</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ansari+MA%22">Ansari MA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Bakheet+SA%22">Bakheet SA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Algonaiah+MA%22">Algonaiah MA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Mazroua+HA%22">Al-Mazroua HA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alomar+HA%22">Alomar HA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Sarawi+WS%22">Sarawi WS</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almutairi+MM%22">Almutairi MM</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aldossari+AA%22">Aldossari AA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Saquib+Q%22">Saquib Q</searchLink>; Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Algarzae+NK%22">Algarzae NK</searchLink>; Department of Physiology, College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Mahmoud+MA%22">Mahmoud MA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hussein+MH%22">Hussein MH</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ahmad+SF%22">Ahmad SF</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia. fashaikh@ksu.edu.sa.
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        Text: English
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      – TitleFull: S3I-201, a STAT3 Inhibitor, Inhibits Proinflammatory Mediator Signalling in CD19 and CD45R/B220 Cells in a Mouse Model of Multiple Sclerosis.
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