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Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.

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Title: Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.
Authors: Ruthirakuhan M; Sunnybrook Research Institute, University of Toronto, 2075 Bayview Avenue, EG04, Toronto, ON, M2N 3M5, Canada., Mills M; Sunnybrook Research Institute, University of Toronto, 2075 Bayview Avenue, EG04, Toronto, ON, M2N 3M5, Canada., Rosenberg P; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Haughey N; Tulane University School of Medicine, New Orleans, LA, USA., Mintzer J; Ralph H. Johnson VA Health Care System, Medical University of South Carolina, Charleston, USA., Craft S; Wake Forest University, Winston-Salem, NC, USA., Herrmann N; Sunnybrook Research Institute, University of Toronto, 2075 Bayview Avenue, EG04, Toronto, ON, M2N 3M5, Canada., Lerner AJ; University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Levey AI; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA, USA., Padala PR; Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock, USA., Porsteinsson A; University of Rochester School of Medicine and Dentistry, Rochester, New York, USA., van Dyck CH; Yale School of Medicine, New Haven, CT, USA., Shade D; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Lanctôt KL; Sunnybrook Research Institute, Toronto, ON, Canada. krista.lanctot@sunnybrook.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. krista.lanctot@sunnybrook.ca.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. krista.lanctot@sunnybrook.ca.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 May 25. Date of Electronic Publication: 2026 May 25.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.
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  Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2026 May 25. <i>Date of Electronic Publication: </i>2026 May 25.
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