Neutrophil Extracellular Traps Are Associated With Early Neurological Deterioration in Patients With Acute Ischemic Stroke Receiving Intravenous Thrombolysis: A Prospective Cohort Study.
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| Title: | Neutrophil Extracellular Traps Are Associated With Early Neurological Deterioration in Patients With Acute Ischemic Stroke Receiving Intravenous Thrombolysis: A Prospective Cohort Study. |
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| Authors: | Pei L; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zhang W; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zhang D; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zhao Z; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zhou Y; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zong C; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Wang J; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Chen Z; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Zhao H; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Qian Y; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Tian M; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Liu X; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Fang H; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Rong W; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Liu K; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Li Y; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Xu X; Department of Clinical Sciences Liverpool School of Tropical Medicine Liverpool UK., Leng X; Department of Medicine and Therapeutics The Chinese University of Hong Kong China., Ning MM; Clinical Proteomics Research Center and Cardio-Neurology Clinic, Department of Neurology, Massachusetts General Hospital Harvard Medical School Boston MA USA., Wang D; Department of Clinical Sciences Liverpool School of Tropical Medicine Liverpool UK., Xu Y; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China., Song B; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China. |
| Source: | Journal of the American Heart Association [J Am Heart Assoc] 2026 Jun 02; Vol. 15 (11), pp. e045163. Date of Electronic Publication: 2026 May 25. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42179266 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Neutrophil Extracellular Traps Are Associated With Early Neurological Deterioration in Patients With Acute Ischemic Stroke Receiving Intravenous Thrombolysis: A Prospective Cohort Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pei+L%22">Pei L</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zong+C%22">Zong C</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Qian+Y%22">Qian Y</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Tian+M%22">Tian M</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Fang+H%22">Fang H</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Rong+W%22">Rong W</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Liu+K%22">Liu K</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Department of Clinical Sciences Liverpool School of Tropical Medicine Liverpool UK.<br /><searchLink fieldCode="AU" term="%22Leng+X%22">Leng X</searchLink>; Department of Medicine and Therapeutics The Chinese University of Hong Kong China.<br /><searchLink fieldCode="AU" term="%22Ning+MM%22">Ning MM</searchLink>; Clinical Proteomics Research Center and Cardio-Neurology Clinic, Department of Neurology, Massachusetts General Hospital Harvard Medical School Boston MA USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Department of Clinical Sciences Liverpool School of Tropical Medicine Liverpool UK.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.<br /><searchLink fieldCode="AU" term="%22Song+B%22">Song B</searchLink>; Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.; The NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou China.; Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2026 Jun 02; Vol. 15 (11), pp. e045163. <i>Date of Electronic Publication: </i>2026 May 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101580524 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2047-9980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479980%22">20479980 </searchLink><i>NLM ISO Abbreviation: </i>J Am Heart Assoc <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1161/JAHA.125.045163 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e045163 Titles: – TitleFull: Neutrophil Extracellular Traps Are Associated With Early Neurological Deterioration in Patients With Acute Ischemic Stroke Receiving Intravenous Thrombolysis: A Prospective Cohort Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pei L – PersonEntity: Name: NameFull: Zhang W – PersonEntity: Name: NameFull: Zhang D – PersonEntity: Name: NameFull: Zhao Z – PersonEntity: Name: NameFull: Zhou Y – PersonEntity: Name: NameFull: Zong C – PersonEntity: Name: NameFull: Wang J – PersonEntity: Name: NameFull: Chen Z – PersonEntity: Name: NameFull: Zhao H – PersonEntity: Name: NameFull: Qian Y – PersonEntity: Name: NameFull: Tian M – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Fang H – PersonEntity: Name: NameFull: Rong W – PersonEntity: Name: NameFull: Liu K – PersonEntity: Name: NameFull: Li Y – PersonEntity: Name: NameFull: Xu X – PersonEntity: Name: NameFull: Leng X – PersonEntity: Name: NameFull: Ning MM – PersonEntity: Name: NameFull: Wang D – PersonEntity: Name: NameFull: Xu Y – PersonEntity: Name: NameFull: Song B IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 06 Text: 2026 Jun 02 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2047-9980 Numbering: – Type: volume Value: 15 – Type: issue Value: 11 Titles: – TitleFull: Journal of the American Heart Association Type: main |
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