View in EDS HTML Full Text PDF Full Text

A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects.

Saved in:
Bibliographic Details
Title: A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects.
Authors: Deng K; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Huang J; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China., Wu Q; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Xie J; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Yang X; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Yang S; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Liu L; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Gong Y; Gynecology Department, The Third Xiangya Hospital, Central South University, Changsha, China., Shen W; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China., Cai L; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China., Yang G; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China., Guo C; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 May 07; Vol. 17, pp. 1821901. Date of Electronic Publication: 2026 May 07 (Print Publication: 2026).
Publication Type: Clinical Trial; Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42181873
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Deng+K%22">Deng K</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Xie+J%22">Xie J</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; Gynecology Department, The Third Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Shen+W%22">Shen W</searchLink>; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China.<br /><searchLink fieldCode="AU" term="%22Cai+L%22">Cai L</searchLink>; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Guo+C%22">Guo C</searchLink>; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 May 07; Vol. 17, pp. 1821901. <i>Date of Electronic Publication: </i>2026 May 07 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Clinical Trial; Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42181873
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3389/fphar.2026.1821901
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1821901
    Titles:
      – TitleFull: A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Deng K
      – PersonEntity:
          Name:
            NameFull: Huang J
      – PersonEntity:
          Name:
            NameFull: Wu Q
      – PersonEntity:
          Name:
            NameFull: Xie J
      – PersonEntity:
          Name:
            NameFull: Yang X
      – PersonEntity:
          Name:
            NameFull: Yang S
      – PersonEntity:
          Name:
            NameFull: Liu L
      – PersonEntity:
          Name:
            NameFull: Gong Y
      – PersonEntity:
          Name:
            NameFull: Shen W
      – PersonEntity:
          Name:
            NameFull: Cai L
      – PersonEntity:
          Name:
            NameFull: Yang G
      – PersonEntity:
          Name:
            NameFull: Guo C
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 07
              M: 05
              Text: 2026 May 07
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 1663-9812
          Numbering:
            – Type: volume
              Value: 17
          Titles:
            – TitleFull: Frontiers in pharmacology
              Type: main
ResultId 1