A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects.
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| Title: | A randomized controlled phase Ia clinical trial to evaluate the safety, tolerability and pharmacokinetic characteristics of tofacitinib tartrate cream (HZ-J001) in healthy Chinese subjects. |
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| Authors: | Deng K; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Huang J; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China., Wu Q; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Xie J; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Yang X; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Yang S; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Liu L; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China., Gong Y; Gynecology Department, The Third Xiangya Hospital, Central South University, Changsha, China., Shen W; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China., Cai L; Hubei Chengtian Pharmaceutical Co., Ltd., Tianmen, China., Yang G; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China., Guo C; Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 May 07; Vol. 17, pp. 1821901. Date of Electronic Publication: 2026 May 07 (Print Publication: 2026). |
| Publication Type: | Clinical Trial; Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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