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Gamma-glutamyl metformin inhibits renal cell carcinoma progression by activating AMPK signaling pathway.

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Title: Gamma-glutamyl metformin inhibits renal cell carcinoma progression by activating AMPK signaling pathway.
Authors: Lv Z; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China., Zhang LS; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Aisha A; The Third Central Clinical College of Tianjin Medical University, Tianjin, China., Wang TH; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Cui HY; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Tang S; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China., Zhang JH; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China., Chang F; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China., Wu WS; Department of Urology, Affiliated Hospital of Jianghan University, Wuhan, China., Li LY; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Zhang ZS; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China.; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Chen FM; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China.; Department of Urology, Affiliated Hospital of Jianghan University, Wuhan, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 May 07; Vol. 17, pp. 1807987. Date of Electronic Publication: 2026 May 07 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Gamma-glutamyl metformin inhibits renal cell carcinoma progression by activating AMPK signaling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Lv+Z%22">Lv Z</searchLink>; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhang+LS%22">Zhang LS</searchLink>; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Aisha+A%22">Aisha A</searchLink>; The Third Central Clinical College of Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+TH%22">Wang TH</searchLink>; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Cui+HY%22">Cui HY</searchLink>; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Tang+S%22">Tang S</searchLink>; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhang+JH%22">Zhang JH</searchLink>; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chang+F%22">Chang F</searchLink>; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wu+WS%22">Wu WS</searchLink>; Department of Urology, Affiliated Hospital of Jianghan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Li+LY%22">Li LY</searchLink>; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhang+ZS%22">Zhang ZS</searchLink>; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China.; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chen+FM%22">Chen FM</searchLink>; Department of Urology, Central Hospital, Tianjin University/Tianjin Third Central Hospital, Tianjin, China.; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Tianjin, China.; Department of Urology, Affiliated Hospital of Jianghan University, Wuhan, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 May 07; Vol. 17, pp. 1807987. <i>Date of Electronic Publication: </i>2026 May 07 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 May 07
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